Evidence map›Paper›PMID 22810979›Full record

ReviewCurrent gastroenterology reports2012

Autoimmune enteropathy: a review and update of clinical management.

Nicole M Gentile, Joseph A Murray, Darrell S Pardi

Open access · greenAbstract readReview
In one paragraph

Review in Current gastroenterology reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 2 syntheses or guidelines pooled it, 142 citations in OpenAlex.

  1. Pooled it
  2. Microscopic enteritis: Bucharest consensus.World journal of gastroenterology · 2015
    Guideline
  3. Article
  4. Article
  5. Harnessing mRNA-lipid nanoparticles as innovative therapies for autoimmune diseases.Molecular therapy. Methods & clinical development · 2025
    Review
  6. Article
  7. Liver Involvement in Celiac Disease and Immune-Mediated Diseases of the Small Bowel.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Non-celiac Enteropathies.Current gastroenterology reports · 2025
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Refractory Celiac Disease: What the Gastroenterologist Should Know.International journal of molecular sciences · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nicole M GentileDivision of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. gentile.nicole@mayo.edu
Joseph A Murray
Darrell S Pardi
Mayo Clinic · USMayo Clinic in Arizona · US

Funding

EPIDEMIOLOGY OF CELIAC DISEASE--A POPULATION BASED STUDYR01DK057892 · NIDDK · MAYO CLINIC ROCHESTER · PI MURRAY, JOSEPH A · 2000 to 2010
$3.9M
NIDDK NIH HHS DK57892NIDDK NIH HHS R01 DK057892
6 · The paper itself

Abstract

Autoimmune enteropathy (AIE) is a rare condition characterized by intractable diarrhea, histologic changes on small intestinal biopsy, and failed response to dietary manipulation that also may present with extraintestinal manifestations. In many patients, immunosuppressive therapies are necessary. Although AIE is more common in infants, adult involvement has also been documented. Much of what is known about AIE has been gathered from case reports and small case series; therefore, more research in this evolving field is needed. IPEX (immunodysregulation polyendocrinopathy enteropathy X-linked syndrome) and APECED (autoimmune phenomena, polyendocrinopathy, candidiasis, and ectodermal dystrophy) are systemic forms of AIE.

Indexed as

Autoimmune DiseasesAdultHumansImmunosuppressive AgentsInfantIntestinal DiseasesParenteral NutritionImmunosuppressive Agents

Identifiers

PMID22810979
PMCPMC3912565
OpenAlexW2041367623

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.