ArticleJournal of physiology and biochemistry2013
Plasma levels of interleukin-6 and interleukin-18 after an acute physical exercise: relation with post-exercise energy intake in twins.
Article in Journal of physiology and biochemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03295968 (The Role of IL-6 in Exercise-Induced Anorexia in Normal-weight Boys), which is not on this map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Role of IL-6 in Exercise-Induced Anorexia in Normal-weight Boys
Who cites it
15 citing papers in PubMed, 41 citations in OpenAlex.
- Acute Responses to High-Intensity Back Squats with Bilateral Blood Flow Restriction.International journal of environmental research and public health · 2023Trial
- Exercise as a Therapeutic Strategy for Obesity: Central and Peripheral Mechanisms.Metabolites · 2024Review
- Effect of serum concentrations of IL-6 and TNF-α on brain structure in anorexia nervosa: a combined cross-sectional and longitudinal study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Proinflammatory cytokines interleukin-18 and interleukin-6 mediate anorexia induction by trichothecene deoxynivalenol and its congeners.Frontiers in veterinary science · 2024Article
- Innate immunity changes in soccer players after whole-body cryotherapy.BMC sports science, medicine & rehabilitation · 2022Article
- Effects of whole-body cryotherapy on the innate and adaptive immune response in cyclists and runners.Immunologic research · 2020Article
- Effect of Acute Sprint Exercise on Myokines and Food Intake Hormones in Young Healthy Men.International journal of molecular sciences · 2020Article
- Compensatory eating behaviors in male and female rats in response to exercise training.American journal of physiology. Regulatory, integrative and comparative physiology · 2020Article
- High intensity resistance training causes muscle damage and increases biomarkers of acute kidney injury in healthy individuals.PloS one · 2018Article
- Potential involvement of lactate and interleukin-6 in the appetite-regulatory hormonal response to an acute exercise bout.Journal of applied physiology (Bethesda, Md. : 1985) · 2017Article
- Decreased Appetite after High-Intensity Exercise Correlates with Increased Plasma Interleukin-6 in Normal-Weight and Overweight/Obese Boys.Current developments in nutrition · 2017Article
- The Effect of Exercise Intensity on Total PYY and GLP-1 in Healthy Females: A Pilot Study.Journal of nutrition and metabolism · 2017Article
- Effects of exercise at individual anaerobic threshold and maximal fat oxidation intensities on plasma levels of nesfatin-1 and metabolic health biomarkers.Journal of physiology and biochemistry · 2015Article
- Associations of interleukin-6 with vegetative but not affective depressive symptoms in terminally ill cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2013Article
- A Systematic Review of the Acute Effects of Exercise on Immune and Inflammatory Indices in Untrained Adults.Sports medicine - openReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increased interleukin-6 (IL-6) plasma levels have been described to occur during physical exercise. A relative reduction in energy intake after physical activity has also been reported after exercise, indicating a possible involvement of IL-6 as an anorexigenic factor. Given the possible effect of interleukins on appetite, we assessed whether a controlled physical activity bout is related with changes in IL-6, IL-6 soluble receptor (IL-6sR), gp130 and interleukin-18 (IL-18) plasma levels, as well as their relation with post-exercise energy intake. A co-twin intervention study was carried out with five young male monozygotic twin pairs. One co-twin performed 45 min of submaximal exercise on a treadmill near the anaerobic threshold ending with 7 min at 90 % VO(2) max, while his co-twin remained non-active. Ad libitum energy intake was tested through a carbohydrate-rich meal test. Venous blood samples were drawn at baseline, immediately after exercise and after the meal ingestion. Plasma concentrations of IL-6, IL-6sR, gp130 and IL-18 were measured via ELISA. IL-6 plasma levels increased after physical activity bout (2.6-fold change; p = 0.04). A less marked trend, although still significant, was observed for plasma levels of IL-6sR and gp130. Plasma levels of IL-18 did not significantly change during exercise. The twins who exercised exhibited significantly lower energy intake (181 versus 1,195 kcal; p = 0.04), compared to the co-twins who remained resting. The present study in monozygotic twins shows increased IL-6 plasma levels after acute physical exercise with a significant reduction in energy intake, supporting a linkage between IL-6 and acute post-exercise eating behaviour.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.