Evidence map›Paper›PMID 22810464›Full record

SynthesisEuropean journal of nutrition2013

The relationship between high-fat dairy consumption and obesity, cardiovascular, and metabolic disease.

Mario Kratz, Ton Baars, Stephan Guyenet

4 registry-linked trialsAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European journal of nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 146 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
146citing papers in PubMed, 15 pooled it
31.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01803633 naactive not recruitingnot on this map

Effects of Dairy Fat on Postprandial Inflammation- Phase 2

TypeinterventionalSponsorUniversity of California, DavisRan2012 to 2027Enrolled20ConditionsMetabolic Syndrome, ObesityArmsCheddar cheese, Vegan cheese
NCT01811329 naactive not recruitingnot on this map

Effects of Dairy Fat on Postprandial Inflammation- Phase 1

TypeinterventionalSponsorUniversity of California, DavisRan2013 to 2027Enrolled38ConditionsMetabolic Syndrome, ObesityArmsDairy fat, Dairy fat + MFGM, Palm fat, Palm fat + MFGM
NCT02980094 nacompletednot on this map

Effects of Inclusion of Sunflower Oil, Vitamin E and Selenium in the Diet of Dairy Cows on Milk Composition and Its Influence on Nutrition and Health of Elderly

TypeinterventionalSponsorEduardo FerriolliRan2011 to 2011Enrolled132ConditionsNutrient Deficiency, Age-Related Immunodeficiency, Vitamin E Deficiency, Selenium DeficiencyArmsMilk Antioxidant group(A), Milk Oil group(O), Milk Antioxidant and oil(AO), Milk Control group(C)
NCT03577119 nacompletednot on this mapstarted 2018, after this paper: background citation

Full-fat Yogurt and Glucose Tolerance

TypeinterventionalSponsorUniversity of Vermont Medical CenterRan2018 to 2022Enrolled13ConditionsPre-DiabetesArmsFull-fat yogurt, Non-fat yogurt
3 · Its place in the literature

Who cites it

146 citing papers in PubMed, 15 syntheses or guidelines pooled it, 419 citations in OpenAlex.

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  6. Effects of total fat intake on bodyweight in children.The Cochrane database of systematic reviews · 2018
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  7. Effects of total fat intake on bodyweight in children.The Cochrane database of systematic reviews · 2018
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  13. Effects of total fat intake on body weight.The Cochrane database of systematic reviews · 2015
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86 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Mario KratzDivision of Public Health Sciences, Cancer Prevention Program, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, Mail Stop M4-B402, Seattle, WA, 98109, USA. mkratz@fhcrc.org
Ton Baars
Stephan Guyenet
Fred Hutch Cancer Center · USResearch Institute of Organic Agriculture · BEUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo comprehensively review the data on the relationship between the consumption of dairy fat and high-fat dairy foods, obesity, and cardiometabolic disease.

methodsWe have conducted a systematic literature review of observational studies on the relationship between dairy fat and high-fat dairy foods, obesity, and cardiometabolic disease. We have integrated these findings with data from controlled studies showing effects of several minor dairy fatty acids on adiposity and cardiometabolic risk factors, and data on how bovine feeding practices influence the composition of dairy fat.

resultsIn 11 of 16 studies, high-fat dairy intake was inversely associated with measures of adiposity. Studies examining the relationship between high-fat dairy consumption and metabolic health reported either an inverse or no association. Studies investigating the connection between high-fat dairy intake and diabetes or cardiovascular disease incidence were inconsistent. We discuss factors that may have contributed to the variability between studies, including differences in (1) the potential for residual confounding; (2) the types of high-fat dairy foods consumed; and (3) bovine feeding practices (pasture- vs. grain-based) known to influence the composition of dairy fat.

conclusionsThe observational evidence does not support the hypothesis that dairy fat or high-fat dairy foods contribute to obesity or cardiometabolic risk, and suggests that high-fat dairy consumption within typical dietary patterns is inversely associated with obesity risk. Although not conclusive, these findings may provide a rationale for future research into the bioactive properties of dairy fat and the impact of bovine feeding practices on the health effects of dairy fat.

Indexed as

AdiposityBody WeightCardiovascular DiseasesCholesterolDairy ProductsDiabetes Mellitus, Type 2Dietary FatsGlucose Tolerance TestHumansInflammationInsulin ResistanceMetabolic SyndromeObesityRisk FactorsCholesterolDietary Fats

Identifiers

PMID22810464
OpenAlexW2077936854

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.