Evidence map›Paper›PMID 22810424›Full record

ArticleLab on a chip2012

Single-cell electroporation using a multifunctional pipette.

Alar Ainla, Shijun Xu, Nicolas Sanchez, Gavin D M Jeffries, Aldo Jesorka

Abstract read
In one paragraph

Article in Lab on a chip, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Alar AinlaDepartment of Chemical and Biological Engineering, Chalmers University of Technology, S-41296 Göteborg, Sweden.
Shijun Xu
Nicolas Sanchez
Gavin D M Jeffries
Aldo Jesorka
Chalmers University of Technology · SESanofi (France) · FR

Funding

Single Cell ElectroporationR01GM066018 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WEBER, STEPHEN G. · 2003 to 2014
$3.1M
NIGMS NIH HHS GM R01-066018NIGMS NIH HHS R01 GM066018
6 · The paper itself

Abstract

We present here a novel platform combination, using a multifunctional pipette to individually electroporate single-cells and to locally deliver an analyte, while in their culture environment. We demonstrate a method to fabricate low-resistance metallic electrodes into a PDMS pipette, followed by characterization of its effectiveness, benefits and limits in comparison with an external carbon microelectrode.

Indexed as

AnimalsCell Culture TechniquesCell Line, TumorDimethylpolysiloxanesElectrodesElectroporationMiceMicrofluidic Analytical TechniquesRatsSingle-Cell AnalysisbaysilonDimethylpolysiloxanes

Identifiers

PMID22810424
PMCPMC3805499
OpenAlexW2027069386

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.