ReviewJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2012
Laparoscopic versus open appendectomy for complicated and uncomplicated appendicitis in children.
Review in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 10 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
49 citing papers in PubMed, 10 syntheses or guidelines pooled it, 164 citations in OpenAlex.
- Selective non-operative management of post-appendectomy abscesses in children: a comprehensive systematic review and pairwise meta-analysis.Pediatric surgery international · 2026Pooled it
- Appendectomy versus antibiotic treatment for acute appendicitis.The Cochrane database of systematic reviews · 2024Pooled it
- Aspiration versus peritoneal lavage in appendicitis: a meta-analysis.World journal of emergency surgery : WJES · 2021Pooled it
- Management of appendiceal mass and abscess in children; early appendectomy or initial non-operative treatment? A systematic review and meta-analysis.Surgical endoscopy · 2020Pooled it
- Peritoneal irrigation vs suction alone during pediatric appendectomy for perforated appendicitis: A meta-analysis.Medicine · 2019Pooled it
- Laparoscopic versus open appendectomy in pediatric patients with complicated appendicitis: a meta-analysis.Surgical endoscopy · 2019Pooled it
- Diagnosis and management of acute appendicitis. EAES consensus development conference 2015.Surgical endoscopy · 2016Guideline
- Pooled it
- Laparoscopic approach to appendectomy reduces the incidence of short- and long-term post-operative bowel obstruction: systematic review and pooled analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2014Pooled it
- Pooled it
- Laparoscopic appendectomy for complicated appendicitis in children: does the post-operative peritoneal drain make any difference? A pilot prospective randomised controlled trial.Pediatric surgery international · 2022Trial
- Post appendectomy complications and associated factors among children in Amhara region, ethiopia: Multi-center retrospective follow up study.Langenbeck's archives of surgery · 2025Article
- Laparoscopic versus open appendicectomy performed by adult general surgeons in pre-teenage years children: a single-centre experience.Annals of the Royal College of Surgeons of England · 2025Article
- Risk Factors for Postoperative Intra-Abdominal Abscess in Pediatric Perforated Appendicitis Following Laparoscopic Appendectomy: A Multicenter Analysis.Children (Basel, Switzerland) · 2024Article
- Appendicitis in children: correlation between the surgical and histological diagnosis.Pediatric surgery international · 2024Observational
- Perforated Appendicitis in Children: Management, Microbiology, and Antibiotic Stewardship.Paediatric drugs · 2024Review
- Article
- Self-Locking Polymeric Clips Are Safe for the Closure of Appendiceal Stump in Laparoscopic Appendectomy.Medicina (Kaunas, Lithuania) · 2023Article
- The uncharted severity of complications after appendectomy for acute appendicitis in children: results from 348 consecutive patients.Updates in surgery · 2022Article
- Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAppendectomy is one of the most common emergency operations performed in the pediatric population. The aim of this pooled analysis is to compare the outcome from complicated appendicitis (CA) and uncomplicated appendicitis (UA) following laparoscopic appendectomy (LA) and open appendectomy (OA) in children.
methodsA systematic literature search was performed. Primary outcome measures were incidence of complications, intra-abdominal abscess, and wound infection. Secondary outcomes were length of operation, length of hospital stay, incidence of bowel obstruction, and readmission.
resultsSeventy-three thousand one hundred fifty appendectomies for UA and 34,474 appendectomies for CA were included. For UA, the only significant difference between the groups was a reduced length of hospital stay following LA. LA in CA was associated with reduced complications (pooled odds ratio [POR] = 0.53; P < 0.05), wound infections (POR = 0.42; P < 0.05), length of hospital stay (WMD = -0.67; P < 0.05), and bowel obstruction episodes (POR = 0.8; P < 0.05), but an increased incidence of intra-abdominal abscess and length of operation.
conclusionPooled analysis demonstrates that, in children with uncomplicated acute appendicitis, LA is associated with a reduced hospital stay but broad equivalence in postoperative morbidity when compared with the conventional approach. Although overall morbidity is reduced when the laparoscopic approach is utilized, in cases of CA, the risk of intra-abdominal abscess is increased.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.