Evidence map›Paper›PMID 22809894›Full record

ArticleDrug and alcohol dependence2013

Symptoms of depression and PTSD are associated with elevated alcohol demand.

James G Murphy, Ali M Yurasek, Ashley A Dennhardt, Jessica R Skidmore, Meghan E McDevitt-Murphy, James MacKillop, Matthew P Martens

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.

  1. Pooled it
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  7. Reward deprivation is associated with elevated alcohol demand in emerging adults.Journal of the experimental analysis of behavior · 2025
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  18. Addiction is driven by excessive goal-directed drug choice under negative affect: translational critique of habit and compulsion theory.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020
    Review
  19. Review
  20. Gender Differences in Harmful Use of Alcohol Among Korean Adults.Osong public health and research perspectives · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

James G MurphyDepartment of Psychology, University of Memphis, Memphis, TN 38152, United States. jgmurphy@memphis.edu
Ali M Yurasek
Ashley A Dennhardt
Jessica R Skidmore
Meghan E McDevitt-Murphy
James MacKillop
Matthew P Martens
University of Memphis · USUniversity of Georgia · USUniversity of Missouri · US

Funding

Enhancing Alcoholism Pharmacotherapy Research via Behavioral EconomicsK23AA016936 · NIAAA · UNIVERSITY OF GEORGIA · PI MACKILLOP, JAMES · 2008 to 2012
$805k
Family-Enhanced Cognitive Behavioral Therapy for Comorbid PTSD and Alcohol Abuse.K23AA016120 · NIAAA · UNIVERSITY OF MEMPHIS · PI MCDEVITT-MURPHY, MEGHAN E. · 2007 to 2011
$742k
NIAAA NIH HHS K23 AA016120NIAAA NIH HHS K23 AA016936
6 · The paper itself

Abstract

backgroundBehavioral economic demand curves measure individual differences in motivation for alcohol and have been associated with problematic patterns of alcohol use, but little is known about the variables that may contribute to elevated demand. Negative visceral states have been theorized to increase demand for alcohol and to contribute to excessive drinking patterns, but little empirical research has evaluated this possibility. The present study tested the hypothesis that symptoms of depression and PTSD would be uniquely associated with elevated alcohol demand even after taking into account differences in typical drinking levels.

methodAn Alcohol Purchase Task (APT) was used to generate a demand curve measure of alcohol reinforcement in a sample of 133 college students (50.4% male, 64.4% Caucasian, 29.5% African-American) who reported at least one heavy drinking episode (5/4 or more drinks in one occasion for a man/woman) in the past month. Participants also completed standard measures of alcohol consumption and symptoms of depression and PTSD.

resultsRegression analyses indicated that symptoms of depression were associated with higher demand intensity (alcohol consumption when price=0; ΔR(2)=.05, p=.002) and lower elasticity (ΔR(2)=.04, p=.03), and that PTSD symptoms were associated with all five demand curve metrics (ΔR(2)=.04-.07, ps<.05).

conclusionsThese findings provide support for behavioral economic models of addiction that highlight the role of aversive visceral states in increasing the reward value of alcohol and provide an additional theoretical model to explain the association between negative affect and problematic drinking patterns.

Indexed as

StudentsUniversitiesAdolescentAlcohol DrinkingCross-Sectional StudiesDepressionFemaleHumansMaleStress Disorders, Post-TraumaticYoung Adult

Identifiers

PMID22809894
PMCPMC3775331
OpenAlexW2010136266

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.