ArticleBiotechnology for biofuels2012
Biodiesel biorefinery: opportunities and challenges for microbial production of fuels and chemicals from glycerol waste.
Article in Biotechnology for biofuels, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- Microbial Conversion of Glycerol Into 1,3-Propanediol by Fermentation: Review of Fundamentals and Operational Strategies.Microbial biotechnology · 2025Review
- High production of enantiopure (R,R)-2,3-butanediol from crude glycerol by Klebsiella pneumoniae with an engineered oxidative pathway and a two-stage agitation strategy.Microbial cell factories · 2024Article
- Trends in PHA Production by Microbially Diverse and Functionally Distinct Communities.Microbial ecology · 2023Review
- Rewiring of glycerol metabolism in Escherichia coli for effective production of recombinant proteins.Biotechnology for biofuels · 2020Article
- Metabolism, morphology and transcriptome analysis of oscillatory behavior of Clostridium butyricum during long-term continuous fermentation for 1,3-propanediol production.Biotechnology for biofuels · 2020Article
- Selective oxidation of alkyl and aryl glyceryl monoethers catalysed by an engineered and immobilised glycerol dehydrogenase.Chemical science · 2020Article
- From Organic Wastes to Bioplastics: Feasibility of Nonsterile Poly(3-hydroxybutyrate) Production byACS omega · 2020Article
- Nitrogen as the major factor influencing gene expression inBiotechnology reports (Amsterdam, Netherlands) · 2020Article
- Valorisation of crude glycerol to value-added products: Perspectives of process technology, economics and environmental issues.Biotechnology reports (Amsterdam, Netherlands) · 2020Review
- Article
- Biodiesel's trash is a biorefineries' treasure: the use of "dirty" glycerol as an industrial fermentation substrate.World journal of microbiology & biotechnology · 2019Review
- Improved electrocompetence and metabolic engineering ofEngineering in life sciences · 2019Article
- Formate-removing inoculum dominated by Methanobacterium congolense supports succinate production from crude glycerol fermentation.Journal of industrial microbiology & biotechnology · 2019Article
- Production of Added-Value Chemical Compounds through Bioconversions of Olive-Mill Wastewaters Blended with Crude Glycerol by aMolecules (Basel, Switzerland) · 2019Article
- Impact of acetolactate synthase inactivation on 1,3-propanediol fermentation by Klebsiella pneumoniae.PloS one · 2019Article
- Streptomyces albulus yields ε-poly-L-lysine and other products from salt-contaminated glycerol waste.Journal of industrial microbiology & biotechnology · 2018Article
- Production of p-amino-L-phenylalanine (L-PAPA) from glycerol by metabolic grafting of Escherichia coli.Microbial cell factories · 2018Article
- An Overview of Biorefinery Derived Platform Chemicals from a Cellulose and Hemicellulose Biorefinery.Clean technologies and environmental policy · 2018Article
- Engineering Yarrowia lipolytica to Simultaneously Produce Lipase and Single Cell Protein from Agro-industrial Wastes for Feed.Scientific reports · 2018Article
- Electro-fermentation triggering population selection in mixed-culture glycerol fermentation.Microbial biotechnology · 2018Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The considerable increase in biodiesel production worldwide in the last 5 years resulted in a stoichiometric increased coproduction of crude glycerol. As an excess of crude glycerol has been produced, its value on market was reduced and it is becoming a "waste-stream" instead of a valuable "coproduct". The development of biorefineries, i.e. production of chemicals and power integrated with conversion processes of biomass into biofuels, has been singled out as a way to achieve economically viable production chains, valorize residues and coproducts, and reduce industrial waste disposal. In this sense, several alternatives aimed at the use of crude glycerol to produce fuels and chemicals by microbial fermentation have been evaluated. This review summarizes different strategies employed to produce biofuels and chemicals (1,3-propanediol, 2,3-butanediol, ethanol, n-butanol, organic acids, polyols and others) by microbial fermentation of glycerol. Initially, the industrial use of each chemical is briefly presented; then we systematically summarize and discuss the different strategies to produce each chemical, including selection and genetic engineering of producers, and optimization of process conditions to improve yield and productivity. Finally, the impact of the developments obtained until now are placed in perspective and opportunities and challenges for using crude glycerol to the development of biodiesel-based biorefineries are considered. In conclusion, the microbial fermentation of glycerol represents a remarkable alternative to add value to the biodiesel production chain helping the development of biorefineries, which will allow this biofuel to be more competitive.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.