ArticleAmerican journal on intellectual and developmental disabilities2012
Family environment and behavior problems in children, adolescents, and adults with fragile X syndrome.
Article in American journal on intellectual and developmental disabilities, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Parental Expressed Emotion and Behavioural Outcomes in Autistic Children and Adolescents: A Systematic Review.Child psychiatry and human development · 2025Pooled it
- Pooled it
- Public Health Literature Review of Fragile X Syndrome.Pediatrics · 2017Pooled it
- Phenotypic variability of Fragile-X syndrome in Asian population: A systematic review.Intractable & rare diseases research · 2026Review
- The comparison of expressed emotion of parents of individuals with fragile X syndrome to other intellectual disabilities.Journal of applied research in intellectual disabilities : JARID · 2023Article
- Change in Behavior Problems from Childhood Through Adolescence for Children with Fragile X Syndrome.Journal of autism and developmental disorders · 2022Article
- Advancing artificial intelligence-assisted pre-screening for fragile X syndrome.BMC medical informatics and decision making · 2022Article
- Verbal Ability, Behavior Problems, and Mother-Child Relationship Quality in Autism Spectrum Disorder.Journal of autism and developmental disorders · 2022Article
- Change in Maladaptive Behavior Affects Intergenerational Relationships in Fragile X Syndrome.American journal on intellectual and developmental disabilities · 2022Article
- The Role of Parenting Practices on the Parent Perceived Impact of Child Oral Health on Family Wellbeing.International journal of environmental research and public health · 2022Article
- Family as a Context for Child Development: Mothers with the FMR1 Premutation and Their Children with Fragile X Syndrome.Seminars in speech and language · 2021Review
- Artificial intelligence-assisted phenotype discovery of fragile X syndrome in a population-based sample.Genetics in medicine : official journal of the American College of Medical Genetics · 2021Article
- Dynamics of Parental Opioid Use and Children's Health and Well-Being: An Integrative Systems Mapping Approach.Frontiers in psychology · 2021Article
- Friendships and social participation as markers of quality of life of adolescents and adults with fragile X syndrome and autism.Autism : the international journal of research and practice · 2019Article
- Of Men and Mice: Modeling the Fragile X Syndrome.Frontiers in molecular neuroscience · 2018Article
- Automated screening for Fragile X premutation carriers based on linguistic and cognitive computational phenotypes.Scientific reports · 2017Article
- Executive Functioning Mediates the Effect of Behavioral Problems on Depression in Mothers of Children With Developmental Disabilities.American journal on intellectual and developmental disabilities · 2017Article
- Change in the Behavioral Phenotype of Adolescents and Adults with FXS: Role of the Family Environment.Journal of autism and developmental disorders · 2016Article
- Family function, Parenting Style and Broader Autism Phenotype as Predicting Factors of Psychological Adjustment in Typically Developing Siblings of Children with Autism Spectrum Disorders.Iranian journal of psychiatry · 2014Article
- Distance delivery of a parent-implemented language intervention for young boys with fragile X syndrome.Autism & developmental language impairmentsArticle
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
We examine how the family environment is associated with aspects of the Fragile X syndrome phenotype during childhood, adolescence, and adulthood. Mothers of children (n = 48), adolescents (n = 85), and adults (n = 34) with Fragile X syndrome participated in a multisite study. For children and adults with Fragile X syndrome, the presence of warmth and positivity and the absence of criticism were associated with fewer behavior problems. Although a higher level of criticism was significantly associated with greater behavior problems, there were only trend-level associations between levels of warmth and positivity and behavior problems during the adolescent years. The provision of family psychoeducation programs, which can reduce parental criticism, would likely benefit both the individual with Fragile X syndrome and the family.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.