Evidence map›Paper›PMID 22808425›Full record

ArticleBiomedical optics express2012

Multispectral scanning time-resolved fluorescence spectroscopy (TRFS) technique for intravascular diagnosis.

Hongtao Xie, Julien Bec, Jing Liu, Yang Sun, Matthew Lam, Diego R Yankelevich, Laura Marcu

Abstract read
In one paragraph

Article in Biomedical optics express, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hongtao XieUniversity of California, Davis, Department of Biomedical Engineering, 451 Health Sciences Drive, Davis, CA 95616, USA.
Julien Bec
Jing Liu
Yang Sun
Matthew Lam
Diego R Yankelevich
Laura Marcu

Funding

Time-Resolved Spectroscopy of Unstable Arterial PlaquesR01HL067377 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MARCU, LAURA · 2001 to 2015
$5.2M
NHLBI NIH HHS R01 HL067377
6 · The paper itself

Abstract

This study describes a scanning time-resolved fluorescence spectroscopy (TRFS) system designed to continuously acquire fluorescence emission and to reconstruct fluorescence lifetime images (FLIM) from a luminal surface by using a catheter-based optical probe with rotary joint and pull-back device. The ability of the system to temporally and spectrally resolve the fluorescence emission from tissue was validated using standard dyes and tissue phantoms (e.g., ex vivo pig aorta phantom). Current results demonstrate that this system is capable to reliably resolve the fluorescence emission of multiple fluorophores located in the lumen; and suggest its potential for intravascular detection of distinct biochemical features of atherosclerotic plaques.

Indexed as

(110.7170) Ultrasound(170.6510) Spectroscopy, tissue diagnostics(170.6935) Tissue characterization(300.6500) Spectroscopy, time-resolved

Identifiers

PMID22808425
PMCPMC3395478

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.