Evidence map›Paper›PMID 22808292›Full record

ReviewInternational journal of clinical and experimental pathology2012

ALK-immunoreactive neoplasms.

Parham Minoo, Huan-You Wang

Abstract readReview
In one paragraph

Review in International journal of clinical and experimental pathology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Unveiling Cancer.Sultan Qaboos University medical journal · 2015
    Article
  15. Article
  16. Increased ALK1 copy number and renal cell carcinoma-a case report.Virchows Archiv : an international journal of pathology · 2014
    Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Parham MinooDepartment of Pathology, University of California San Diego Health Sciences System, La Jolla, CA 92093-0987, USA.
Huan-You Wang
UC San Diego Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextSince the first discovery of anaplastic lymphoma kinase (ALK) in anaplastic large cell lymphoma (ALCL) by Morris et al in 1994, the number of ALK-positive neoplasms, either in the form of translocation or gain-of-function mutations, have been dramatically expanded from ALCL of T- and NK-cell origin, to diffuse large B-cell lymphoma, inflammatory myofibroblastic tumor (IMT), neuroblastoma, non-small cell lung carcinoma (NSCLC), undifferentiated anaplastic thyroid carcinoma, and rare type of sarcomas.

objectiveThis review covers the major aspects of ALK-immunoreactive neoplasms with emphasis on the pathogenesis of ALK-positive neoplasms. The new advances and rapid-evolving practices using ALK inhibitors for therapy are also discussed at the end of this review. DATA SOURCES: ALK(+) articles published in English literature are retrieved and critically reviewed.

conclusionALK(+) neoplasia is a rapidly growing field and the list of ALK(+) neoplasms is being expanded continuously. Accurate and correct diagnosis of ALK(+) neoplasms is of paramount importance in guiding the appropriate treatment in the era of personalized medicine using specific ALK inhibitor.

Indexed as

Anaplastic Lymphoma KinaseAntineoplastic AgentsEnzyme InhibitorsFemaleHumansLymphoma, Large-Cell, AnaplasticMaleMolecular Targeted TherapyNeoplasmsPrecision MedicineReceptor Protein-Tyrosine KinasesALK protein, humanAnaplastic Lymphoma KinaseAntineoplastic AgentsEnzyme InhibitorsReceptor Protein-Tyrosine KinasesALK-positive neoplasmsanaplastic large cell lymphoma (ALCL)Anaplastic lymphoma kinase (ALK)

Identifiers

PMID22808292
PMCPMC3396068
OpenAlexW59923497

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.