Evidence map›Paper›PMID 22807290›Full record

ArticleAngewandte Chemie (International ed. in English)2012

M2 proton channel structural validation from full-length protein samples in synthetic bilayers and E. coli membranes.

Yimin Miao, Huajun Qin, Riqiang Fu, Mukesh Sharma, Thach V Can, Ivan Hung, Sorin Luca, Peter L Gor'kov, William W Brey, Timothy A Cross

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

  1. Review
  2. Article
  3. bioRxiv : the preprint server for biology · 2025
    Article
  4. Solid-state NMR of membrane proteins in situ.Current opinion in structural biology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Pore-Bound Water at the Key Residue Histidine 37 in Influenza A M2.Angewandte Chemie (International ed. in English) · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. M2 amphipathic helices facilitate pH-dependent conformational transition in influenza A virus.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  14. Article
  15. De novo resonance assignment of the transmembrane domain of LR11/SorLA in E. coli membranes.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2020
    Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. CombinedStructure (London, England : 1993) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yimin MiaoDepartment of Chemistry and Biochemistry, Institute of Molecular Biophysics, National High Magnetic Field Lab, Florida State University, Tallahassee, FL 32306, USA.
Huajun Qin
Riqiang Fu
Mukesh Sharma
Thach V Can
Ivan Hung
Sorin Luca
Peter L Gor'kov
William W Brey
Timothy A Cross

Funding

Target IdentificationP01AI074805 · NIAID · FLORIDA STATE UNIVERSITY · PI CROSS, TIMOTHY A · 2009 to 2013
$8.7M
DYNAMIC AND STRUCTURAL ELUCIDATION OF GRAMICIDIN A'R01AI023007 · NIAID · FLORIDA STATE UNIVERSITY · PI CROSS, TIMOTHY A · 1987 to 2014
$5.1M
NIAID NIH HHS AI074805NIAID NIH HHS AI23007NIAID NIH HHS P01 AI074805NIAID NIH HHS R01 AI023007
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell MembraneEscherichia coliLipid BilayersNuclear Magnetic Resonance, BiomolecularProtein ConformationReproducibility of ResultsViral Matrix ProteinsViroporin ProteinsLipid BilayersM2 protein, Influenza A virusViral Matrix ProteinsViroporin Proteins

Identifiers

PMID22807290
PMCPMC3423641

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.