Trial reportClinical orthopaedics and related research2013
The John Insall award: no benefit of minimally invasive TKA on gait and strength outcomes: a randomized controlled trial.
Trial report in Clinical orthopaedics and related research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Comparison of conventional and minimally invasive approaches of primary total knee arthroplasty: a network meta-analysis of randomized controlled trials.BMC musculoskeletal disorders · 2026Pooled it
- The Time Course of Quadriceps Strength Recovery After Total Knee Arthroplasty Is Influenced by Body Mass Index, Sex, and Age of Patients: Systematic Review and Meta-Analysis.Frontiers in medicine · 2022Pooled it
- Better outcomes after minimally invasive surgeries compared to the standard invasive medial parapatellar approach for total knee arthroplasty: a meta-analysis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021Pooled it
- Do outcomes reported in randomised controlled trials of joint replacement surgery fulfil the OMERACT 2.0 Filter? A review of the 2008 and 2013 literature.Systematic reviews · 2017Pooled it
- Comparison of the quadriceps-sparing and subvastus approaches versus the standard parapatellar approach in total knee arthroplasty: a meta-analysis of randomized controlled trials.BMC musculoskeletal disorders · 2015Pooled it
- A meta-analysis of minimally invasive and conventional medial parapatella approaches for primary total knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2015Pooled it
- Post-operative limb position can influence blood loss and range of motion after total knee arthroplasty: a systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2015Pooled it
- Pooled it
- The Comparison between Mini-Subvastus Approach and Medial Parapatellar Approach in TKA: A Prospective Double-Blinded Randomized Controlled Trial.Orthopaedic surgery · 2022Trial
- Effect of different postoperative flexion regimes on the outcomes of total knee arthroplasty: randomized controlled trial.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2017Trial
- The John Insall Award: No Functional Benefit After Unicompartmental Knee Arthroplasty Performed With Patient-specific Instrumentation: A Randomized Trial.Clinical orthopaedics and related research · 2016Trial
- No benefit of patient-specific instrumentation in TKA on functional and gait outcomes: a randomized clinical trial.Clinical orthopaedics and related research · 2014Trial
- Changes in knee pain and walking speed following primary, unilateral total knee arthroplasty and their association: A systematic review and meta-analysis.Osteoarthritis and cartilage open · 2025Review
- Advancements in Total Knee Arthroplasty over the Last Two Decades.Journal of clinical medicine · 2025Review
- Better outcomes after mini-subvastus approach for primary total knee arthroplasty: a Bayesian network meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2020Review
- Analysis of learning curve of minimally invasive total knee arthroplasty: A single surgeon's experience with 4017 cases over a 9-year period.Journal of the Chinese Medical Association : JCMA · 2019Article
- Minimally invasive versus conventional approaches in total knee replacement/arthroplasty: A review of the literature.Journal of orthopaedics · 2018Review
- Gait analysis methodology for the measurement of biomechanical parameters in total knee arthroplasties. A literature review.Journal of orthopaedics · 2018Review
- Medial subvastusEFORT open reviews · 2018Article
- Compromised knee internal rotation in total knee arthroplasty patients during stair climbing.PloS one · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhile some clinical reports suggest minimally invasive surgical (MIS) techniques improve recovery and reduce pain in the first months after TKA, it is unclear whether it improves gait and thigh muscle strength. QUESTIONS/PURPOSES: We hypothesized TKA performed through a mini-subvastus approach would improve subjective and objective and subjective function compared to a standard medial parapatellar approach 2 months after surgery.
methodsWe randomized 40 patients into two groups using either the mini-subvastus approach or standard medial parapatellar approach. Patients were evaluated preoperatively and 2 months after surgery. We assessed subjective functional outcome and quality of life (QOL) using routine questionnaires (SF-12, Knee Society Score [KSS], Knee Injury and Osteoarthritis Outcome Score [KOOS], UCLA activity, patient milestone diary of activities). We determined isometric strength of the thigh muscles and assessed gait with a three-dimensional (3-D) analysis during level walking and stair climbing.
resultsWe observed improvements from preoperatively to 2 months postoperatively in functional scores, QOL, and knee kinematic and kinetic gait parameters during level and stair walking. Isometric quadriceps strength increased in both groups, although remaining lower when compared to sound limbs. We found no differences between the groups in KSS, SF-12, KOOS, UCLA activity, patient milestone diary of activities, isometric quadriceps strength, or 3-D gait parameters, except a marginally higher speed of stair ascent in the MIS group.
conclusionsOur observations suggest an MIS approach does not confer a substantial advantage in early function after TKA. LEVEL OF EVIDENCE: Level I, therapeutic study. See Instructions to Authors for a complete description of levels of evidence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.