Trial reportWorld journal of surgery2012
Randomized controlled trial of tamsulosin for prevention of acute voiding difficulty after rectal cancer surgery.
Trial report in World journal of surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03314025 (Prophylactic Tamsulosin in Prevention of Post-operative Urinary Retention in Men After Transanal Endoscopic Microsurgery), which is not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prophylactic Tamsulosin in Prevention of Post-operative Urinary Retention in Men After Transanal Endoscopic Microsurgery: A Multicenter Randomized, Double-blind, Placebo-controlled Clinical Trial
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Systematic review and meta-analysis of early removal of urinary catheter after colorectal surgery with infraperitoneal anastomosis.Langenbeck's archives of surgery · 2022Pooled it
- Strategies for the removal of short-term indwelling urethral catheters in adults.The Cochrane database of systematic reviews · 2021Pooled it
- Risk factors and development of a nomogram prediction model for urinary dysfunction after laparoscopic radical surgery for rectal cancer.Frontiers in surgery · 2026Article
- Renal Cell Carcinoma with Duodenal Metastasis: Is There a Place for Surgery? A Review.Journal of clinical medicine · 2025Review
- Prophylactic tamsulosin and urinary retention rates following elective colorectal surgery: a retrospective cohort study.International journal of colorectal disease · 2022Article
- The risk factors for urinary dysfunction after autonomic nerve-preserving rectal cancer surgery: a multicenter retrospective study at Yokohama Clinical Oncology Group (YCOG1307).International journal of colorectal disease · 2019Article
- Evaluation the efficacy of prophylactic tamsulosin in preventing acute urinary retention and other obstructive urinary symptoms following colporrhaphy surgery.Journal of family medicine and primary care · 2019Article
- Preventive effect of tamsulosin on postoperative urinary retention in neurosurgical patients.Surgical neurology international · 2017Article
- Integrative review on the non-invasive management of lower urinary tract symptoms in men following treatments for pelvic malignancies.International journal of clinical practice · 2015Review
- Risk factors and preventive measures for acute urinary retention after rectal cancer surgery.World journal of surgery · 2015Article
- Urinary catheter management.Clinics in colon and rectal surgery · 2013Review
- The incidence and risk factors for postoperative urinary retention in neurosurgical patients.Surgical neurology international · 2013Article
- Medical and non-medical interventions for post-operative urinary retention prevention: network meta-analysis and risk-benefit analysis.Therapeutic advances in urologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe conducted a randomized clinical trial to investigate the efficacy of the selective α(1A)-adrenoceptor antagonist tamsulosin in preventing acute voiding difficulty after rectal cancer surgery.
methodsA total of 94 rectal cancer patients with an International Prostate Symptom Score (IPSS) of ≤7 were randomly assigned (1:1) to the tamsulosin group (0.2 mg/day orally for 7 days) (n = 47) or the control group (n = 47). The primary endpoint was the reinsertion rate of the urinary catheter after its removal on postoperative day (POD) 3. The secondary endpoints included the maximum (Qmax) and average (Qavg) urinary flow rates on POD 3, and the voided volume (VV), residual urine volume (RU), and IPSS on POD 7. Analyses were based on an intention-to-treat population.
resultsThe reinsertion rate of the urinary catheter in the tamsulosin group was similar to that in the control group (23.4 vs. 21.3 %, respectively; p = 0.804). The postoperative voiding parameters and IPSS were not better in the tamsulosin group than in the control group after adjustments were made for the baseline measurements with analysis of covariance (Qmax, p = 0.537; Qavg, p = 0.399; VV, p = 0.645; RU, p = 0.703; IPSS, p = 0.761). Multivariate analysis revealed that being male was the only independent risk factor for reinsertion of the urinary catheter (odds ratio 0.239; 95 % confidence interval 0.069-0.823; p = 0.023).
conclusionsThis controlled trial showed that tamsulosin at 0.2 mg/day does not prevent acute voiding difficulty after rectal cancer surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.