ArticleWorld journal of microbiology & biotechnology2012
Comparison of the structural characterization and biological activity of acidic polysaccharides from Cordyceps militaris cultured with different media.
Article in World journal of microbiology & biotechnology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 65 citations in OpenAlex.
- Bombyx mori-Hosted Cordyceps militaris Polysaccharides: Structural Characterization and Antibacterial Activity of Native and Sulfated Derivatives.Chemistry & biodiversity · 2026Article
- Structural Characterization and Antioxidant Properties of a Novel Polysaccharide Isolated fromACS omega · 2025Article
- Chitosan Nanoparticle-EncapsulatedInternational journal of molecular sciences · 2025Article
- Review
- Unique Bioactives from Zombie Fungus (Nutrients · 2023Review
- Rich d-Fructose-Containing Polysaccharide Isolated fromACS omega · 2022Article
- Enhancement of Stability and Antioxidant Activity of Mulberry Anthocyanins Through Succinic Acid Acylation.Food technology and biotechnology · 2022Article
- Structural Characterization of Mannoglucan Isolated fromACS omega · 2022Article
- Improvement in the Blood Urea Nitrogen and Serum Creatinine Using New Cultivation ofEvidence-based complementary and alternative medicine : eCAM · 2022Article
- Structural Elucidation and Activities ofFrontiers in nutrition · 2022Review
- Immunomodulatory and Antioxidant Effects of Polysaccharides from the Parasitic FungusBioMed research international · 2020Article
- Structural characterization of polysaccharides fromRSC advances · 2018Article
- Transcriptome-wide analysis reveals the progress of Cordyceps militaris subculture degeneration.PloS one · 2017Article
- Rhf1 gene is involved in the fruiting body production of Cordyceps militaris fungus.Journal of industrial microbiology & biotechnology · 2015Article
- Purification, chemical characterization and radical scavenging activities of alkali-extracted polysaccharide fractions isolated from the fruit bodies of Tricholoma matsutake.World journal of microbiology & biotechnology · 2013Article
- Antioxidant and Hemolysis Protective Effects of Polyphenol-Rich Extract from Mulberry Fruits.Pharmacognosy magazineArticle
- In vitro and In vivo Antioxidant Activity of Flavonoid Extracted from Mulberry Fruit (Morus alba L.).Pharmacognosy magazineArticle
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Authors and funding
7 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Two acidic polysaccharide fractions, CM-jd-CPS2 and CM-jd(Y)-CPS2, were isolated from the fruiting bodies of cultured Cordyceps militaris grown on solid rice medium and silkworm pupa, respectively, by hot-water extraction, ethanol precipitation and fractionation using ion-exchange column (DEAE-cellulose-52) and gel-filtration column (Sephadex G-100) chromatography. Their structural characterizations were performed by gas chromatography and fourier-transform infrared spectroscopy. Some differences existed between their structures, which indicated that culture media could influence the structure of polysaccharides of C. militaris. The antioxidant activities of CM-jd-CPS2 and CM-jd(Y)-CPS2 were evaluated by various methods in vitro. They had strong 2,2-diphenyl-1-picrylhydrazyl radical-scavenging activity and ferrous ion-chelating capacity, but moderate reducing power. The antioxidant activities of CM-jd(Y)-CPS2 were slightly higher than those of CM-jd-CPS2. These two acidic fractions were evaluated for proliferation of mouse splenocyte activity in vitro. They both possessed does-dependent mitogenic effects on mouse splenocytes, and could synergistically promote murine T- and B-lymphocytes induced by Con A and LPS. CM-jd(Y)-CPS2 exhibited stronger stimulatory activities upon immunomodulation than CM-jd-CPS2. These results are beneficial for the interpretation of the connection between polysaccharide structures and their biological activities.
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