Evidence map›Paper›PMID 22805424›Full record

ReviewClinical pharmacology and therapeutics2012

Failure of proton pump inhibitors to treat GERD in neonates and infants: a question of drug, diagnosis, or design.

V Shakhnovich, R M Ward, G L Kearns

Abstract readReview
In one paragraph

Review in Clinical pharmacology and therapeutics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Review
  3. Article
  4. Appropriateness of proton pump inhibitors use in noncritically ill hospitalized children in a tertiary hospital in Saudi Arabia.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  5. Widespread use of gastric acid inhibitors in infants: Are they needed? Are they safe?World journal of gastrointestinal pharmacology and therapeutics · 2016
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

V ShakhnovichDepartment of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.
R M Ward
G L Kearns

Funding

Childrens Mercy Hospital Fellowship Program in Pediatric PharmacologyT32HD069038 · NICHD · CHILDREN'S MERCY HOSP (KANSAS CITY, MO) · PI Laura B Ramsey, Jonathan Wagner · 2011 to 2026
$3.1M
NCATS NIH HHS L40 TR000598NICHD NIH HHS T32 HD069038
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gastroesophageal RefluxHumansInfantInfant, NewbornInfant, Newborn, DiseasesOff-Label UsePractice Patterns, Physicians'Proton Pump InhibitorsTreatment FailureProton Pump Inhibitors

Identifiers

PMID22805424
PMCPMC7704114

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.