Evidence map›Paper›PMID 22805095›Full record

ReviewVeterinary ophthalmology2012

Optical coherence tomography for the evaluation of retinal and optic nerve morphology in animal subjects: practical considerations.

Gillian J McLellan, Carol A Rasmussen

Abstract readReview
In one paragraph

Review in Veterinary ophthalmology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 69 citations in OpenAlex.

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  14. Assessment of the pigeon (Journal of veterinary science · 2021
    Article
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  17. Retinal Features in Cynomolgus Macaques (Comparative medicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gillian J McLellanDepartment of Ophthalmology & Visual Sciences, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53792, USA. mclellan@vetmed.wisc.edu
Carol A Rasmussen
University of Wisconsin–Madison · US

Funding

UW Vision Research Core - Administrative CoreP30EY016665 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI ROBERT W NICKELLS · 2005 to 2026
$12.6M
Structural and Functional Characterization of a Novel Model for Glaucoma ResearchK08EY018609 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI MCLELLAN, GILLIAN JANE · 2008 to 2012
$860k
NEI NIH HHS K08 EY018609NEI NIH HHS K08EY018609NEI NIH HHS P30EY0016665NEI NIH HHS P30 EY016665
6 · The paper itself

Abstract

Optical coherence tomography (OCT) is a noninvasive, noncontact imaging technique capable of producing high-resolution images of the retina and optic nerve. These images provide information that is useful for following the progression and/or resolution of posterior segment disease. Rapid advances in OCT technology allow the acquisition of increasingly detailed images, approaching the original goal of providing in vivo histopathology. Increases in scan acquisition speeds and axial resolution enhance the clinical diagnostic value of this modality. Adapting instrumentation designed for use in human patients for use in animals can be challenging. Each species has a unique set of adjustments that need to be made but it is possible to obtain reproducible, high-quality OCT images in a variety of animals, including rodents, dogs, cats, pigs, and monkeys. Deriving quantitative measurements from OCT instruments is hindered by software algorithm errors in detecting the edges of the distinct retinal layers. These segmentation errors occur in scans of human eyes as well in other species and arise with similar frequency with each of the different OCT instruments. Manual segmentation methods to derive optic nerve head and other structural indices have been developed for several species.

Indexed as

AnimalsOptic NerveRetinaRetinal DiseasesTomography, Optical Coherence

Identifiers

PMID22805095
PMCPMC3459243
OpenAlexW1560654742

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.