ArticleGenes & development2012
No simpler than mammals: axon and dendrite regeneration in Drosophila.
Article in Genes & development, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- A 3D Fiber-Hydrogel Based Non-Viral Gene Delivery Platform Reveals that microRNAs Promote Axon Regeneration and Enhance Functional Recovery Following Spinal Cord Injury.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- Inhibition of microRNA-711 limits angiopoietin-1 and Akt changes, tissue damage, and motor dysfunction after contusive spinal cord injury in mice.Cell death & disease · 2019Article
- Human retinal ganglion cell axon regeneration by recapitulating developmental mechanisms: effects of recruitment of the mTOR pathway.Development (Cambridge, England) · 2019Article
- Characterization of cell lines derived from the southern armyworm, Spodoptera eridania.In vitro cellular & developmental biology. Animal · 2018Article
- Insulin signalling promotes dendrite and synapse regeneration and restores circuit function after axonal injury.Brain : a journal of neurology · 2018Article
- Bantam regulates the axonal geometry of Drosophila larval brain by modulating actin regulator enabled.Invertebrate neuroscience : IN · 2018Article
- Article
- Signaling regulations of neuronal regenerative ability.Current opinion in neurobiology · 2014Review
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Authors and funding
3 authors.
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Abstract
Despite important progress made in understanding the mechanisms of axon regeneration, how a neuron responds to an injury and makes a regenerative decision remains unclear. In this issue of Genes & Development, Song and colleagues (pp. 1612-1625) investigate axonal and dendritic regeneration in the Drosophila peripheral nervous system (PNS). With some mechanisms shared with mammals, this study reveals surprisingly complicated regenerative responses in terms of cell type, developmental stage, and mechanism specificity. With forward genetic potential, such invertebrates should be powerful in dissecting the cellular and molecular control of neuronal repair.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.