ArticleApplied and environmental microbiology2012
Bioremediation and tolerance of humans to heavy metals through microbial processes: a potential role for probiotics?
Article in Applied and environmental microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
92 citing papers in PubMed, 2 syntheses or guidelines pooled it, 320 citations in OpenAlex.
- Interventions to reduce cadmium exposure in low- and middle-income countries during pregnancy and childhood: A systematic review.Journal of global health · 2022Pooled it
- Nigerian foods of probiotics relevance and chronic metal exposure: a systematic review.Environmental science and pollution research international · 2020Pooled it
- Human supplementation with Pediococcus acidilactici GR-1 decreases heavy metals levels through modifying the gut microbiota and metabolome.NPJ biofilms and microbiomes · 2022Trial
- Trial
- Engineering the gut microbiome with metal-resistant bacteria could protect Artemia nauplii from cadmium toxicity.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Article
- Eco-Friendly Copper Recovery: Insights to Algal and Agricultural Waste Application.Water environment research : a research publication of the Water Environment Federation · 2026Article
- Gut Microbiota Remodeling after Fecal Microbiota Transplantation Is Associated with Reduced Inflammation and Cardiac Injury in Fluoride-Arsenic Co-Exposed Rats.Biological trace element research · 2026Article
- Probiotic and Microbial Enzymatic Mechanisms for PFAS Detoxification.Probiotics and antimicrobial proteins · 2026Review
- Protective Effects of Lactobacillus curvatus Against Acute Lead and Cadmium Toxicity in Caspian Kutum (Rutilus frisii, Nordmann, 1840): Growth Performance, Chemical Composition, Hematological Characteristics, Serum Biochemical Parameters, and Immune Response.Biological trace element research · 2026Article
- Probiotic detoxification of heavy metals: functional assessment in simulated intestinal andFrontiers in microbiology · 2026Article
- Prophylactic efficacy of probiotics and their metabolites against Staphylococcus epidermidis.BMC microbiology · 2025Article
- The role of the gut microbiome in the associations between lead exposure and child neurodevelopment.Toxicology letters · 2025Review
- Metabolic response of Bacillus spp. to heavy metal stress: pathway alterations and metabolite profiles.Biotechnology letters · 2025Review
- The Effect of the Combination of Probiotics and Heavy Metals From Various Aspects in Humans: A Systematic Review of Clinical Trial Studies.Health science reports · 2025Review
- Mercury and Arctic Char Gill Microbiota Correlation in Canadian Arctic Communities.Microorganisms · 2024Article
- Biocomposite Material Based onPolymers · 2024Article
- Phosphate Uptake and Its Relation to Arsenic Toxicity in Lactobacilli.International journal of molecular sciences · 2024Article
- Mass Spectrometry Applications to Study Human Microbiome.Advances in experimental medicine and biology · 2024Article
- Quantitative Distribution Profile of Cadmium and Lead in Different Organs of Rats and Mitigation of their Accumulation Through Probiotic Treatment.Gut microbes reports · 2024Article
- Control of Bacterial Phenotype and Chromosomal Gene Expression by Single Plasmids ofInternational journal of molecular sciences · 2023Article
32 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The food and water we consume are often contaminated with a range of chemicals and heavy metals, such as lead, cadmium, arsenic, chromium, and mercury, that are associated with numerous diseases. Although heavy-metal exposure and contamination are not a recent phenomenon, the concentration of metals and the exposure to populations remain major issues despite efforts at remediation. The ability to prevent and manage this problem is still a subject of much debate, with many technologies ineffective and others too expensive for practical large-scale use, especially for developing nations where major pollution occurs. This has led researchers to seek alternative solutions for decontaminating environmental sites and humans themselves. A number of environmental microorganisms have long been known for their ability to bind metals, but less well appreciated are human gastrointestinal bacteria. Species such as Lactobacillus, present in the human mouth, gut, and vagina and in fermented foods, have the ability to bind and detoxify some of these substances. This review examines the current understanding of detoxication mechanisms of lactobacilli and how, in the future, humans and animals might benefit from these organisms in remediating environmental contamination of food.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.