Evidence map›Paper›PMID 22798032›Full record

ReviewCurrent gastroenterology reports2012

Clinical implications of enteroadherent Escherichia coli.

Margarita M P Arenas-Hernández, Ygnacio Martínez-Laguna, Alfredo G Torres

Abstract readReview
In one paragraph

Review in Current gastroenterology reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Antimicrobial Resistance and Pathotypes ofAnimals : an open access journal from MDPI · 2024
    Article
  2. Article
  3. Production of a new tetravalent vaccine targeting fimbriae and enterotoxin of enterotoxigenicCanadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Enteropathogenic Escherichia coli: foe or innocent bystander?Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2015
    Review
  13. Adherence and virulence genes of Escherichia coli from children diarrhoea in the Brazilian Amazon.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2015
    Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Margarita M P Arenas-HernándezPosgrado en Microbiología, Centro de Investigaciones en Ciencias Microbiológicas, B. Universidad Autónoma de Puebla, Puebla, México. maguie10@gmail.com
Ygnacio Martínez-Laguna
Alfredo G Torres

Funding

Long Polar Fimbriae of Attaching and Effacing Escherichia coliR01AI079154 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI TORRES, ALFREDO G · 2009 to 2013
$1.9M
E. coli O157: H7 Vaccine DevelopmentR21AI088450 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI TORRES, ALFREDO G · 2011 to 2012
$421k
NIAID NIH HHS AI079154NIAID NIH HHS AI09956001NIAID NIH HHS R01 AI079154NIAID NIH HHS R21 AI088450
6 · The paper itself

Abstract

Pathogenic Escherichia coli that colonize the small intestine primarily cause gastrointestinal illness in infants and travelers. The main categories of pathogenic E. coli that colonize the epithelial lining of the small intestine are enterotoxigenic E. coli, enteropathogenic E. coli, and enteroaggregative E. coli. These organisms accomplish their pathogenic process by a complex, coordinated multistage strategy, including nonintimate adherence mediated by various adhesins. These so called "enteroadherent E. coli" categories subsequently produce toxins or effector proteins that are either secreted to the milieu or injected to the host cell. Finally, destruction of the intestinal microvilli results from the intimate adherence or the toxic effect exerted over the epithelia, resulting in water secretion and diarrhea. In this review, we summarize the current state of knowledge regarding these enteroadherent E. coli strains and the present clinical understanding of how these organisms colonize the human intestine and cause disease.

Indexed as

Bacterial AdhesionDiarrheaEnteropathogenic Escherichia coliEnterotoxigenic Escherichia coliEnterotoxinsEscherichia coli InfectionsHumansIntestinal MucosaIntestine, SmallVirulenceEnterotoxins

Identifiers

PMID22798032
PMCPMC3448025

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.