Evidence map›Paper›PMID 22797996›Full record

ArticleAdvances in nutrition (Bethesda, Md.)2012

Iron and malaria interactions: research needs from basic science to global policy.

Andrew M Prentice, Sharon E Cox

Open access · hybridAbstract readConference Proceedings
In one paragraph

Article in Advances in nutrition (Bethesda, Md.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Iron supplementation for children: Safety in all settings is not clear.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2013
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Andrew M PrenticeMRC International Nutrition Group, London School of Hygiene and Tropical Medicine, London, UK. andrew.prentice@lshtm.ac.uk
Sharon E Cox
MRC Unit the Gambia · GM

Funding

Wellcome Trust 095009
6 · The paper itself

Abstract

The resurgence in interest and concern regarding the potentially malign interactions between iron administration and malaria infections, especially in young children and pregnant women, has generated a research agenda that is both broad and deep. This paper highlights some of the key questions under 5 headings: basic science; clinical science and epidemiology; technological developments; country level planning; and global policy. At a time of unparalleled progress in basic science, which is illuminating the mechanisms by which iron interacts with infectious organisms, it is concluded that there are good medium-term prospects for achieving policy breakthroughs based on a secure foundation of disease-nutrient interactions. However, it is also stressed that there is much that can be done in the interim, especially in relation to health systems and implementation research that can empower systems to integrate iron interventions with programs for malaria prevention, surveillance, and treatment.

Indexed as

Global HealthAnemia, Iron-DeficiencyAntimicrobial Cationic PeptidesBloodChild, PreschoolDietary SupplementsHepcidinsHumansInfantIron, DietaryLiverMalariaResearchAntimicrobial Cationic PeptidesHepcidinsIron, Dietary

Identifiers

PMID22797996
PMCPMC3649730
OpenAlexW2159834803

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.