ReviewAdvances in nutrition (Bethesda, Md.)2012
Vitamin D and influenza.
Review in Advances in nutrition (Bethesda, Md.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- Pooled it
- Randomized Trial of Vitamin D Supplementation to Prevent Seasonal Influenza and Upper Respiratory Infection in Patients With Inflammatory Bowel Disease.Inflammatory bowel diseases · 2019Trial
- Effect of Vitamin D supplementation to reduce respiratory infections in children and adolescents in Vietnam: A randomized controlled trial.Influenza and other respiratory viruses · 2019Trial
- Vitamin D deficiency in community-acquired pneumonia: low levels of 1,25(OH)2 D are associated with disease severity.Respiratory research · 2014Trial
- Vitamin D: A Nutraceutical Supplement at the Crossroad Between Respiratory Infections and COVID-19.International journal of molecular sciences · 2025Review
- Article
- Review
- Vitamin D deficiency in critically ill COVID-19 ARDS patients.Clinical nutrition (Edinburgh, Scotland) · 2022Article
- Vitamin D and the Ability to Produce 1,25(OH)Nutrients · 2022Article
- Micronutrients and bioactive substances: Their potential roles in combating COVID-19.Nutrition (Burbank, Los Angeles County, Calif.) · 2021Review
- Evaluation of vitamin D levels in COVID-19 patients referred to Labafinejad hospital in Tehran and its relationship with disease severity and mortality.Clinical nutrition ESPEN · 2021Article
- In the Age of Viral Pandemic, Can Ingredients Inspired by Human Milk and Infant Nutrition Be Repurposed to Support the Immune System?Nutrients · 2021Review
- The Relationship Between Vitamin D and Infections Including COVID-19: Any Hopes?International journal of general medicine · 2021Review
- Commentary: Myths and facts on vitamin D amidst the COVID-19 pandemic.Metabolism: clinical and experimental · 2020Article
- Oral Supplementation of the Vitamin D Metabolite 25(OH)DNutrients · 2020Article
- Article
- A Basic Review of the Preliminary Evidence That COVID-19 Risk and Severity Is Increased in Vitamin D Deficiency.Frontiers in public health · 2020Review
- Vitamin D Induces Differential Effects on Inflammatory Responses During Bacterial and/or Viral Stimulation of Human Peripheral Blood Mononuclear Cells.Frontiers in immunology · 2020Article
- Vitamin D and Influenza-Prevention or Therapy?International journal of molecular sciences · 2018Review
- Extreme precipitation and emergency room visits for influenza in Massachusetts: a case-crossover analysis.Environmental health : a global access science source · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vitamin D has become increasingly recognized in the literature for its extra-skeletal roles, including an effect on inflammation and the immune response to infection. Our goal was to describe the role of vitamin D in the immune response and implications for the risk of influenza infection in humans. In this review, we first consider literature that provides molecular and genetic support to the idea that vitamin D is related to the adaptive and innate immune responses to influenza infection in vitro and in animal models. We then discuss observational studies and randomized controlled trials of vitamin D supplementation in humans. Finally, we consider some of the knowledge gaps surrounding vitamin D and immune response that must be filled.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.