Evidence map›Paper›PMID 22797822›Full record

ArticleDigestive diseases and sciences2013

Racial disparities in gastrointestinal cancers-related mortality in the U.S. population.

Raxitkumar Jinjuvadia, Kartikkumar Jinjuvadia, Suthat Liangpunsakul

Open access · greenAbstract read
In one paragraph

Article in Digestive diseases and sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

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  15. Trends in racial disparities in pancreatic cancer surgery.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2013
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Raxitkumar JinjuvadiaDepartment of Internal Medicine, Detroit Medical Center, Wayne State University, Detroit, MI, USA.
Kartikkumar Jinjuvadia
Suthat Liangpunsakul
University Hospital and Clinics · USWayne State University · US

Funding

Effect of ethanol on Kupffer cell/hepatocyte interactions and lipid metabolismK08AA016570 · NIAAA · INDIANA UNIVERSITY INDIANAPOLIS · PI LIANGPUNSAKUL, SUTHAT · 2008 to 2012
$659k
Serum Proteomic Profiles as Biomarkers of Abusive Alcohol ConsumptionI01CX000361 · VA · RLR VA MEDICAL CENTER · PI LIANGPUNSAKUL, SUTHAT · 2012 to 2025
–
CSRD VA I01 CX000361NIAAA NIH HHS K08 AA016570
6 · The paper itself

Abstract

backgroundRacial difference in cancer-related mortality has been described in epidemiological studies and evidence points towards higher mortalities in the minorities. To determine the magnitude of racial disparities and sex differences in GI cancer-related mortalities in the US population, we analyzed the data using the third National Health and Nutrition Examination Survey (NHANES III) and related mortality data files.

methodsNHANES III and its related public linked mortality files were used for this study. Our study cohort included subjects who were ≥18 years and were part of the longitudinal mortality follow-up database. The overall GI cancers related mortality was calculated using combined mortality from malignant neoplasm of esophagus, stomach, colon, liver and pancreas. The evaluation of independent predictors of overall GI cancer-related mortality and of each individual GI cancer was carried out using the Cox proportional hazards model.

resultsA total of 13,221 individuals were included in the analyses with the average person year follow-up of 13.9 years. During the follow-up period, 4,146 subjects died. Of these, 199 were from GI-related cancers. Non-Hispanic black (NHB) had significantly higher overall GI-cancer related mortality compared to non-Hispanic white (NHW, adjusted hazard ratio, aHR: 2.31, 95% CI 1.57-3.38, p < 0.001). Subgroup analyses by sex demonstrated higher mortality from gastric, colorectal and primary liver cancer related mortality in NHB men compared to NHW men. Esophageal and pancreatic cancer mortalities were higher in NHB women compared to NHW women.

conclusionOverall GI cancer-related mortality is significantly higher among NHB compared to NHW in the U.S. population.

Indexed as

AdolescentAdultAgedAged, 80 and overFemaleGastrointestinal NeoplasmsHumansMaleMiddle AgedNutrition SurveysRacial GroupsSex FactorsUnited StatesYoung Adult

Identifiers

PMID22797822
PMCPMC3632293
OpenAlexW2078441843

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.