Evidence map›Paper›PMID 22797745›Full record

ReviewJournal of acquired immune deficiency syndromes (1999)2012

Voluntary medical male circumcision: an HIV prevention priority for PEPFAR.

Jason Bailey Reed, Emmanuel Njeuhmeli, Anne Goldzier Thomas, Melanie C Bacon, Robert Bailey, Peter Cherutich, Kelly Curran, Kim Dickson, Tim Farley, Catherine Hankins and 7 more

Abstract readReview
In one paragraph

Review in Journal of acquired immune deficiency syndromes (1999), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 67 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Preventing HIV Among Adolescent Boys and Young Men Through PEPFAR-Supported Voluntary Medical Male Circumcision in 15 Sub-Saharan African Countries, 2018-2021.AIDS education and prevention : official publication of the International Society for AIDS Education · 2023
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Circumcised men's perceptions, understanding and experiences of voluntary medical male circumcision in KwaZulu-Natal, South Africa.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2020
    Article
  15. Article
  16. Article
  17. Article
  18. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 2 countries.

Jason Bailey ReedUS Centers for Disease Control and Prevention, Atlanta, GA, USA. jreed1@cdc.gov
Emmanuel Njeuhmeli
Anne Goldzier Thomas
Melanie C Bacon
Robert Bailey
Peter Cherutich
Kelly Curran
Kim Dickson
Tim Farley
Catherine Hankins
Karin Hatzold
Jessica Justman
Zebedee Mwandi
Luke Nkinsi
Renee Ridzon
Caroline Ryan
Naomi Bock
Centers for Disease Control and Prevention · USUnited States Agency for International Development · USJohns Hopkins University · USNational Aids Control Council · KENational Institutes of Health · USNaval Health Research Center · USUniversity of Illinois Chicago · USCenters for Disease Control and Prevention · KE

Funding

DevelopmentalP30AI082151 · NIAID · RUSH UNIVERSITY MEDICAL CENTER · PI LANDAY, ALAN L · 2009 to 2014
$4.6M
NIAID NIH HHS P30 AI082151
6 · The paper itself

Abstract

As the science demonstrating strong evidence for voluntary medical male circumcision (VMMC) for HIV prevention has evolved, the President's Emergency Plan for AIDS Relief (PEPFAR) has collaborated with international agencies, donors, and partner country governments supporting VMMC programming. Mathematical models forecast that quickly reaching a large number of uncircumcised men with VMMC in strategically chosen populations may dramatically reduce community-level HIV incidence and save billions of dollars in HIV care and treatment costs. Because VMMC is a 1-time procedure that confers life-long partial protection against HIV, programs for adult men are vital short-term investments with long-term benefits. VMMC also provides a unique opportunity to reach boys and men with HIV testing and counseling services and referrals for other HIV services, including treatment. After formal recommendations by WHO in 2007, priority countries have pursued expansion of VMMC. More than 1 million males have received VMMC thus far, with the most notable successes coming from Kenya's Nyanza Province. However, a myriad of necessary cultural, political, and ethical considerations have moderated the pace of overall success. Because many millions more uncircumcised men would benefit from VMMC services now, US President Barack Obama committed PEPFAR to provide 4.7 million males with VMMC by 2014. Innovative circumcision methods-such as medical devices that remove the foreskin without injected anesthesia and/or sutures-are being rigorously evaluated. Incorporation of safe innovations into surgical VMMC programs may provide the opportunity to reach more men more quickly with services and dramatically reduce HIV incidence for all.

Indexed as

Circumcision, MaleCommunicable Disease ControlDisease Transmission, InfectiousGlobal HealthHIV InfectionsHumansInternational CooperationMaleNational Health ProgramsPublic-Private Sector PartnershipsUnited States

Identifiers

PMID22797745
PMCPMC3663585
OpenAlexW2033053875

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.