ArticleParasitology research2012
Larvicidal, pupicidal, repellent and adulticidal activity of Citrus sinensis orange peel extract against Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus (Diptera: Culicidae).
Article in Parasitology research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 121 citations in OpenAlex.
- Effectiveness of plant-based repellents against different Anopheles species: a systematic review.Malaria journal · 2019Pooled it
- Toxicity of emulsions, high and low energy nanoemulsions of orange essential oil and d-limonene to3 Biotech · 2026Article
- Mosquitocidal Activity and Enzyme Inhibition of Citrus sinensis Essential Oil Against Anopheles gambiae: In Vivo and In Silico Insights.Neotropical entomology · 2026Article
- Larvicide activity of yeast-encapsulated orange oil againstCurrent research in parasitology & vector-borne diseases · 2025Article
- Chemical Composition of Essential Oil fromInsects · 2024Article
- Citrus-Based Bio-Insect Repellents-A Review on Historical and Emerging Trends in Utilizing Phytochemicals of Citrus Plants.Journal of toxicology · 2024Review
- Plumeria alba flower extract-mediated synthesis of recyclable chitosan-coated cadmium nanoparticles for pest control and dye degradation.Bioprocess and biosystems engineering · 2023Article
- Nanoliposomes containing limonene and limonene-rich essential oils as novel larvicides against malaria and filariasis mosquito vectors.BMC complementary medicine and therapies · 2022Article
- Bioguided Phytochemical Study ofMolecules (Basel, Switzerland) · 2022Article
- High larvicidal efficacy of yeast-encapsulated orange oil against Aedes aegypti strains from Brazil.Parasites & vectors · 2021Article
- Yeast-encapsulated essential oils: a new perspective as an environmentally friendly larvicide.Parasites & vectors · 2020Article
- Antidengue potential of leaf extracts ofHeliyon · 2019Article
- Lichen Parmelia sulcata mediated synthesis of gold nanoparticles: an eco-friendly tool against Anopheles stephensi and Aedes aegypti.Environmental science and pollution research international · 2019Article
- Larvicidal Compounds Extracted fromMolecules (Basel, Switzerland) · 2019Article
- Insecticidal activities ofToxicology reports · 2019Article
- Antioxidant and Larvicidal Activity of Areal Parts ofJournal of arthropod-borne diseases · 2018Article
- Enhanced larvicidal, antibacterial, and photocatalytic efficacy of TiOEnvironmental science and pollution research international · 2018Article
- Larvicidal and ovicidal activity ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2017Article
- Larvicidal activity of Syzygium aromaticum (L.) Merr and Citrus sinensis (L.) Osbeck essential oils and their antagonistic effects with temephos in resistant populations of Aedes aegypti.Memorias do Instituto Oswaldo Cruz · 2016Article
- Multipurpose effectiveness of Couroupita guianensis-synthesized gold nanoparticles: high antiplasmodial potential, field efficacy against malaria vectors and synergy with Aplocheilus lineatus predators.Environmental science and pollution research international · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mosquitoes are the carriers of severe and well-known illnesses such as malaria, arboviral encephalitis, dengue fever, chikunguniya fever, West Nile virus and yellow fever. These diseases produce significant morbidity and mortality in humans and livestock around the world. The present study explored the effects of orange peel ethanol extract of Citrus sinensis on larvicidal, pupicidal, repellent and adulticidal activity against Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus. The orange peel material was shade dried at room temperature and powdered coarsely. From orange peel, 300 g powdered was macerated with 1 L of ethanol sequentially for a period of 72 h each and filtered. The yields of the orange peel ethanol crude extract of C. sinensis 13.86 g, respectively. The extracts were concentrated at reduced temperature on a rotary vacuum evaporator and stored at a temperature of 4 °C. The larvicidal, pupicidal and adult mortality was observed after 24 h of exposure; no mortality was observed in the control group. For C. sinensis, the median lethal concentration values (LC(50)) observed for the larvicidal and pupicidal activities against mosquito vector species A. stephensi first to fourth larval instars and pupae were 182.24, 227.93, 291.69, 398.00 and 490.84 ppm; A. aegypti values were 92.27, 106.60, 204.87, 264.26, 342.45, 436.93 and 497.41 ppm; and C. quinquefasciatus values were 244.70, 324.04, 385.32, 452.78 and 530.97 ppm, respectively. The results of maximum repellent activity were observed at 450 ppm in ethanol extracts of C. sinensis and the mean complete protection time ranged from 150 to 180 min was tested. The ethanol extract of C. sinensis showed 100% repellency in 150 min and showed complete protection in 90 min at 350 ppm against A. stephensi, A. aegypti and C. quinquefasciatus, respectively. The adult mortality was found in ethanol extract of C. sinensis with the LC(50) and LC(90) values of 272.19 and 457.14 ppm, A. stephensi; 289.62 and 494.88 ppm, A. aegypti; and 320.38 and 524.57 ppm, respectively. These results suggest that the orange peel extracts of C. sinensis have the potential to be used as an ideal eco-friendly approach for the control of the vector control programmes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.