ArticleJournal of insect physiology2012
Duration and dose-dependency of female sexual receptivity responses to seminal fluid proteins in Aedes albopictus and Ae. aegypti mosquitoes.
Article in Journal of insect physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed, 74 citations in OpenAlex.
- Transcriptional response of spermathecal secretory cells to mating and receipt of seminal fluid proteins iniScience · 2026Article
- The microbiota impacts life history traits and mating success in malebioRxiv : the preprint server for biology · 2026Article
- Recombinant venom proteins in insect seminal fluid reduce female lifespan.Nature communications · 2025Article
- Agent-based modelling reveals feedback loops and non-linearity between mating system evolution and disease dynamics.PloS one · 2025Article
- Deafness due to loss of a TRPV channel eliminates mating behavior inProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Sperm Storage and Use Following Multiple Insemination inInsects · 2024Article
- Mating of unfed, engorged, and partially to fully gravid Aedes aegypti (Diptera: Culicidae) female mosquitoes in producing viable eggs.Parasites & vectors · 2024Article
- Sex peptide receptor is not required for refractoriness to remating or induction of egg laying in Aedes aegypti.Genetics · 2024Article
- Neurobiology and Changing Ecosystems: Mechanisms Underlying Responses to Human-Generated Environmental Impacts.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Current Status of Omics Studies Elucidating the Features of Reproductive Biology in Blood-Feeding Insects.Insects · 2023Review
- wMel Wolbachia alters female post-mating behaviors and physiology in the dengue vector mosquito Aedes aegypti.Communications biology · 2023Article
- Fertility decline in female mosquitoes is regulated by theiScience · 2023Article
- Determining the Insemination Status ofCold Spring Harbor protocols · 2022Article
- Insemination inCold Spring Harbor protocols · 2022Article
- Interspecific mating bias may drivePNAS nexus · 2022Article
- Could SterileInsects · 2022Article
- Seminal fluid proteins induce transcriptome changes in the Aedes aegypti female lower reproductive tract.BMC genomics · 2021Article
- The impact of mating and sugar feeding on blood-feeding physiology and behavior in the arbovirus vector mosquito Aedes aegypti.PLoS neglected tropical diseases · 2021Article
- Spatial and temporal population dynamics of male and female Aedes albopictus at a local scale in Medellín, Colombia.Parasites & vectors · 2021Article
- Suppression of female fertility inProceedings of the National Academy of Sciences of the United States of America · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Male mosquitoes transfer seminal fluid proteins (hereafter 'SFPs') during mating. These proteins can have profound effects on female behavior in the yellow fever mosquito Aedes aegypti and the Asian tiger mosquito Aedes albopictus. SFPs are thought to be responsible for female refractoriness to mating in both species. However, only limited information is available about the duration of induced refractoriness or the quantity of SFPs required to be effective in Ae. albopictus. Here, we tested the duration of the effect of SFPs on female refractory behavior for both Aedes species. Additionally, we determined the lowest SFP dose required to induce female refractory behavior in Ae. aegypti. Virgin females were injected intra-thoracically with doses ranging from 0.25 to 0.008 equivalents of one male's SFP amount. Our results demonstrate high sensitivity of female Ae. aegypti and Ae. albopictus to SFPs of their own species, with the majority of females becoming refractory at doses ≥ 0.031 male-equivalents after injection into the hemocoel. This effect was long-lasting in both species; none of the injected females were inseminated when presented with males of their own species 30 to 34 days post-injection, whereas most saline-injected control females mated at this time point. These results will aid future work to characterize individual SFPs involved in post-mating refractoriness in these two species. Moreover, they show that as is the situation in the mosquito Anopheles gambiae, and unlike Drosophila melanogaster, sperm are not required for the maintenance of a sexual refractoriness response in Ae. aegypti and Ae. albopictus.
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