ReviewProgress in biophysics and molecular biology2012
Is information a proper observable for biological organization?
Review in Progress in biophysics and molecular biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- The phenotypic reversion of cancer: Experimental evidences on cancer reversibility through epigenetic mechanisms (Review).Oncology reports · 2024Review
- Is Cancer Reversible? Rethinking Carcinogenesis Models-A New Epistemological Tool.Biomolecules · 2023Review
- Article
- Paradoxical Behavior of Oncogenes Undermines the Somatic Mutation Theory.Biomolecules · 2022Article
- Multi-Cellular Immunological Interactions Associated With COVID-19 Infections.Frontiers in immunology · 2022Article
- From Wingspread to CLARITY: a personal trajectory.Nature reviews. Endocrinology · 2021Review
- The Thermodynamic Consequences of Parkinson's Disease.Frontiers in neurology · 2021Review
- Emergence of informative higher scales in biological systems: a computational toolkit for optimal prediction and control.Communicative & integrative biology · 2020Article
- Over a century of cancer research: Inconvenient truths and promising leads.PLoS biology · 2020Article
- Information, programme, signal: dead metaphors that negate the agency of organisms.Interdisciplinary science reviews : ISR · 2020Article
- Low-Digit and High-Digit Polymers in the Origin of Life.Life (Basel, Switzerland) · 2019Article
- Endocrine disruptors - putting the mechanistic cart before the phenomenological horse.Nature reviews. Endocrinology · 2018Review
- The Double-Aspect of Life.Biology · 2018Article
- Modeling mammary organogenesis from biological first principles: Cells and their physical constraints.Progress in biophysics and molecular biology · 2016Review
- The biological default state of cell proliferation with variation and motility, a fundamental principle for a theory of organisms.Progress in biophysics and molecular biology · 2016Review
- Toward a theory of organisms: Three founding principles in search of a useful integration.Progress in biophysics and molecular biology · 2016Review
- In search of principles for a Theory of Organisms.Journal of biosciences · 2015Article
- Cancer Metastases: So Close and So Far.Journal of the National Cancer Institute · 2015Article
- Environmental Epigenetics and a Unified Theory of the Molecular Aspects of Evolution: A Neo-Lamarckian Concept that Facilitates Neo-Darwinian Evolution.Genome biology and evolution · 2015Review
- Epigenetics and the evolution of Darwin's Finches.Genome biology and evolution · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
In the last century, jointly with the advent of computers, mathematical theories of information were developed. Shortly thereafter, during the ascent of molecular biology, the concept of information was rapidly transferred into biology at large. Several philosophers and biologists have argued against adopting this concept based on epistemological and ontological arguments, and also, because it encouraged genetic determinism. While the theories of elaboration and transmission of information are valid mathematical theories, their own logic and implicit causal structure make them inimical to biology, and because of it, their applications have and are hindering the development of a sound theory of organisms. Our analysis concentrates on the development of information theories in mathematics and on the differences between these theories regarding the relationship among complexity, information and entropy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.