Evidence map›Paper›PMID 22796151›Full record

ArticleSchizophrenia research2012

Comparison of putative intermediate phenotypes in schizophrenia patients with and without obsessive-compulsive disorder: examining evidence for the schizo-obsessive subtype.

Anna R Docherty, Michael J Coleman, Xiawei Tu, Curtis K Deutsch, Nancy R Mendell, Deborah L Levy

Abstract readComparative Study
In one paragraph

Article in Schizophrenia research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Cross-Disorder Psychiatric Genomics.Current behavioral neuroscience reports · 2016
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anna R DochertyMinneapolis Veterans Affairs Medical Center, Research 116A Building 68, One Veterans Drive, Minneapolis, MN 55417, USA. AnnaDocherty@mail.missouri.edu
Michael J Coleman
Xiawei Tu
Curtis K Deutsch
Nancy R Mendell
Deborah L Levy

Funding

Research Training: Psychiatric &Statistical GeneticsT32MH020030 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI HERMINE H MAES, MICHAEL CHURTON NEALE · 1999 to 2026
$6.7M
PLEIOTROPIC EFFECTS OF GENES LINKED TO SCHIZOPHRENIAR01MH071523 · NIMH · MCLEAN HOSPITAL · PI LEVY, DEBORAH L · 2006 to 2010
$2.9M
Endophenotype-genotype associations in first-degree relatives of people with schiF31MH092081 · NIMH · UNIVERSITY OF MISSOURI-COLUMBIA · PI DOCHERTY, ANNA R. · 2010 to 2011
$60k
NIMH NIH HHS F31 MH092081NIMH NIH HHS MH071523NIMH NIH HHS R01 MH071523NIMH NIH HHS T32 MH020030
6 · The paper itself

Abstract

Obsessive-compulsive symptoms or obsessive-compulsive disorder (OCD) is estimated to occur in up to 30% of patients with schizophrenia. Whether this subgroup of patients is cognitively, affectively, or physiologically distinct remains unclear. 204 schizophrenia patients, 15 who also met criteria for a diagnosis of OCD, and 147 healthy controls were examined on several intermediate phenotypes. The patient groups did not differ from each other except that the co-morbid group exhibited an elevated rate of eye-tracking dysfunction. Results suggest that OCD-co-morbid patients did not comprise a distinct subgroup based on the measures studied here, although systematic assessment of larger cohorts is warranted.

Indexed as

PhenotypeSchizophrenic PsychologyAdultCognition DisordersCraniofacial AbnormalitiesDiagnostic and Statistical Manual of Mental DisordersFemaleHumansMaleMiddle AgedObsessive-Compulsive DisorderPsychotic DisordersSchizophrenia

Identifiers

PMID22796151
PMCPMC3423524

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.