ArticleJournal of the American Chemical Society2012
Iron catalyzed asymmetric oxyamination of olefins.
Article in Journal of the American Chemical Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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The trial behind it
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Who cites it
28 citing papers in PubMed, 189 citations in OpenAlex.
- Copper-Catalyzed Asymmetric Amino Lactonization of Alkenes: Direct Access to Enantioenriched 1,2-Alkylamino Alcohol Derivatives.Journal of the American Chemical Society · 2026Article
- Catalytic Enantioselective Methods for Synthesis of 1,2-Amino Tertiary Alcohols and Their Analogues.Chemical reviews · 2025Review
- Enantioselective 3,4-Oxyamination of 1,3-Dienes Enabled by an Electron-Rich Planar Chiral Rhodium Indenyl Catalyst.Organic letters · 2025Article
- Asymmetric Aziridination of Allylic Carbamates Using Ion-Paired Rhodium Complexes and Extrapolation to C─H Amination of Phenethyl Carbamates.Angewandte Chemie (International ed. in English) · 2025Article
- Intramolecular Carboxyamidation of Alkyne-Tethered O-Acylhydroxamates through Formation of Fe(III)-Nitrenoids.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024Article
- Parallel kinetic resolution of aziridinesChemical science · 2023Article
- Mechanistic Studies of Iron-PyBOX-Catalyzed Olefin Amino-Oxygenation with Functionalized Hydroxylamines.Organometallics · 2023Article
- Regiodivergent Electrophotocatalytic Aminooxygenation of Aryl Olefins.Journal of the American Chemical Society · 2022Article
- The advent of electrophilic hydroxylamine-derived reagents for the direct preparation of unprotected amines.Chemical communications (Cambridge, England) · 2022Review
- Rh(III)-catalyzed Intra- and Intermolecular 3,4-Difunctionalization of 1,3-DienesACS catalysis · 2022Article
- 1,2-Amino oxygenation of alkenes with hydrogen evolution reaction.Nature communications · 2022Article
- Diastereoselective Three-Component 3,4-Amino Oxygenation of 1,3-Dienes Catalyzed by a Cationic Heptamethylindenyl Rhodium(III) Complex.Journal of the American Chemical Society · 2021Article
- Chiral Hypervalent Iodine Catalysis Enables an Unusual Regiodivergent Intermolecular Olefin Aminooxygenation.JACS Au · 2021Article
- Further Developments and Applications of Oxazoline-Containing Ligands in Asymmetric Catalysis.Chemical reviews · 2021Article
- Linear Regression Model Development for Analysis of Asymmetric Copper-Bisoxazoline Catalysis.ACS catalysis · 2021Article
- Copper-Catalyzed 1,2-Amino Oxygenation of 1,3-Dienes: A Chemo-, Regio-, and Site-Selective Three-Component Reaction withACS catalysis · 2019Article
- Ligand Controlled Ir-Catalyzed Regiodivergent Oxyamination of Unactivated Alkenes.Journal of the American Chemical Society · 2019Article
- Recent Advances in the Catalytic Asymmetric Reactions of Oxaziridines.Molecules (Basel, Switzerland) · 2018Review
- Directed, Palladium(II)-Catalyzed Intermolecular Aminohydroxylation of Alkenes Using a Mild Oxidation System.Organic letters · 2018Article
- Practical Synthetic Procedures for the Iron-Catalyzed Intermolecular Olefin Aminohydroxylation Using Functionalized Hydroxylamines.Synthesis · 2016Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The regioselective and enantioselective oxyamination of alkenes with N-sulfonyl oxaziridines is catalyzed by a novel iron(II) bis(oxazoline) complex. This process affords oxazolidine products that can be easily manipulated to yield highly enantioenriched free amino alcohols. The regioselectivity of this process is complementary to that obtained from the analogous copper(II)-catalyzed reaction. Thus, both regioisomers of enantioenriched 1,2-aminoalcohols can be obtained using oxaziridine-mediated oxyamination reactions, and the overall sense of regiochemistry can be controlled using the appropriate choice of inexpensive first-row transition metal catalyst.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.