Evidence map›Paper›PMID 22792084›Full record

ArticleInternational journal of biomedical imaging2012

Quantifying optical microangiography images obtained from a spectral domain optical coherence tomography system.

Roberto Reif, Jia Qin, Lin An, Zhongwei Zhi, Suzan Dziennis, Ruikang Wang

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in International journal of biomedical imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03590899 (Semi-manual Vessel Density Analysis on Optical Coherence Tomography Angiography Images of Healthy Adults), which is not on this map. Cited by 117 papers.

0numbers the graph read from it
0cells of the map it votes in
117citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03590899 completednot on this mapstarted 2017, after this paper: background citation

Semi-manual Vessel Density Analysis on Optical Coherence Tomography Angiography Images of Healthy Adults

TypeobservationalSponsorSemmelweis UniversityRan2017 to 2022Enrolled39ConditionsHealthyArmsOptical coherence tomography angiography (Zeiss Cirrus HD OCT 5000 AngioPlex)
3 · Its place in the literature

Who cites it

117 citing papers in PubMed, 180 citations in OpenAlex.

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57 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Roberto ReifDepartment of Bioengineering, University of Washington, Seattle, WA 98195, USA.
Jia Qin
Lin An
Zhongwei Zhi
Suzan Dziennis
Ruikang Wang
University of Washington · US

Funding

OPTICAL MICROANGIOGRAHY OF CEREBROVASCULAR PERFUSIONR01HL093140 · NHLBI · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2008 to 2017
$4.2M
Volumetric imaging of blood perfusion and tissue morphology in the cochleaR01DC010201 · NIDCD · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2009 to 2013
$2.2M
Label-free optical imaging of 3D structural and functional microcirculationsR01EB009682 · NIBIB · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2009 to 2012
$1.7M
NHLBI NIH HHS R01 HL093140NIBIB NIH HHS R01 EB009682NIDCD NIH HHS R01 DC010201
6 · The paper itself

Abstract

The blood vessel morphology is known to correlate with several diseases, such as cancer, and is important for describing several tissue physiological processes, like angiogenesis. Therefore, a quantitative method for characterizing the angiography obtained from medical images would have several clinical applications. Optical microangiography (OMAG) is a method for obtaining three-dimensional images of blood vessels within a volume of tissue. In this study we propose to quantify OMAG images obtained with a spectral domain optical coherence tomography system. A technique for determining three measureable parameters (the fractal dimension, the vessel length fraction, and the vessel area density) is proposed and validated. Finally, the repeatability for acquiring OMAG images is determined, and a new method for analyzing small areas from these images is proposed.

Identifiers

PMID22792084
PMCPMC3389716
OpenAlexW2052531822

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.