Evidence map›Paper›PMID 22792043›Full record

ArticleTheScientificWorldJournal2012

Sonographic gallbladder abnormality is associated with intravenous immunoglobulin resistance in Kawasaki disease.

Chih-Jen Chen, Fu-Chen Huang, Mao-Meng Tiao, Ying-Hsien Huang, Li-Yan Lin, Hong-Ren Yu, Kuender D Yang, Yi-Chuan Huang, Chih-Cheng Chen, Wei-Chiao Chang and 1 more

Open access · goldAbstract read
In one paragraph

Article in TheScientificWorldJournal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Age-related differences in clinical characteristics of Kawasaki disease.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2021
    Article
  10. Kawasaki Disease Presenting as Acute Acalculous Cholecystitis.Clinical practice and cases in emergency medicine · 2019
    Article
  11. Article
  12. Acute acalculous cholecystitis in children.World journal of gastroenterology · 2018
    Review
  13. Article
  14. Article
  15. Article
  16. Correlation ofOncotarget · 2017
    Article
  17. Article
  18. Pediatric Biliary Interventions in the Native Liver.Seminars in interventional radiology · 2016
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Chih-Jen ChenDepartment of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Fu-Chen Huang
Mao-Meng Tiao
Ying-Hsien Huang
Li-Yan Lin
Hong-Ren Yu
Kuender D Yang
Yi-Chuan Huang
Chih-Cheng Chen
Wei-Chiao Chang
Ho-Chang Kuo
Kaohsiung Chang Gung Memorial Hospital · TWChang Gung University · TWChang Bing Show Chwan Memorial Hospital · TWKaohsiung Medical University Chung-Ho Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveKawasaki disease (KD) is an acute systematic vasculitis in children which causes coronary arterial lesions and hydrops of gallbladder. Our objective is to correlate the clinical significance and influence on disease outcome of patients with gallbladder abnormalities in Kawasaki dissease.

methodsChildren who met KD diagnosis criteria and were admitted for IVIG treatment were retrospectively enrolled for analysis. Patients with abdominal sonography were divided into 2 groups based on the absence (Group A, N = 61) or presence (Group B, N = 16) of gallbladder abnormalities (GBA), defined as hydrops or acalculous cholecystitis. Between the two groups, clinical features, demographic data (including admission days, coronary artery lesions, IVIG resistance), and laboratory data before/after IVIG treatment were collected for analysis.

resultsThe presence of sonographic gallbladder abnormalities is correlated with higher levels of serum CRP, GPT, and neutrophils. It also points to an increased number of IVIG resistance rates in group B. There was no significant statistical difference among clinical features, age, gender, admission days, or coronary artery lesions between the two groups.

conclusionSonographic gallbladder abnormalities are associated with higher CRP, GPT, neutrophil and IVIG resistance in KD. It can be used as a predictor of IVIG resistance in patients with KD.

Indexed as

Acalculous CholecystitisChild, PreschoolC-Reactive ProteinDrug ResistanceEdemaFemaleGallbladderGallbladder DiseasesHumansImmunoglobulins, IntravenousInfantLeukocyte CountMaleMucocutaneous Lymph Node SyndromeNeutrophilsRetrospective StudiesC-Reactive ProteinImmunoglobulins, Intravenous

Identifiers

PMID22792043
PMCPMC3385618
OpenAlexW2108698597

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.