ArticleInfection2012
Causes of death among Danish HIV patients compared with population controls in the period 1995-2008.
Article in Infection, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Excess mortality attributable to AIDS among people living with HIV in high-income countries: a systematic review and meta-analysis.Journal of the International AIDS Society · 2024Pooled it
- Global Burden of Atherosclerotic Cardiovascular Disease in People Living With HIV: Systematic Review and Meta-Analysis.Circulation · 2018Pooled it
- HIV infection as vascular risk: A systematic review of the literature and meta-analysis.PloS one · 2017Pooled it
- Artificial intelligence-based diagnostic model for schizophrenia in individuals living with HIV.Frontiers in psychiatry · 2026Article
- Article
- Disability-adjusted life years associated with chronic comorbidities among people living with and without HIV: Estimating health burden in British Columbia, Canada.PLOS global public health · 2022Article
- Cervical Human Papillomavirus Infection (HPV) and High Oncogenic Risk Genotypes among Women Living with HIV in Asia: A Meta-Analysis.Journal of clinical medicine · 2021Review
- HIV Infection and Related Mental Disorders.Brain sciences · 2021Review
- Excess mortality related to circulatory system diseases and diabetes mellitus among Italian AIDS patients vs. non-AIDS population: a population-based cohort study using the multiple causes-of-death approach.BMC infectious diseases · 2018Article
- Molecular diagnosis of genital tract infections among HIV-positive women in Iran.Iranian journal of microbiology · 2018Article
- Causes of death and mortality trends of all individuals reported with HIV/AIDS in Israel, 1985-2010.Journal of public health (Oxford, England) · 2018Article
- Uniquely altered transcripts are associated with immune preservation in HIV infection.PloS one · 2017Article
- The burden of chronic diseases and cost-of-care in subjects with HIV infection in a Health District of Northern Italy over a 12-year period compared to that of the general population.BMC public health · 2016Article
- Recent Insights Into Cardiovascular Disease (CVD) Risk Among HIV-Infected Adults.Current HIV/AIDS reports · 2016Review
- Ageing with HIV: a multidisciplinary review.Infection · 2015Review
- Clinical course and quality of care in ART-naïve patients newly presenting in a HIV outpatient clinic.Infection · 2014Article
- Echocardiographic screening for pulmonary arterial hypertension in HIV-positive patients.Infection · 2014Article
- Article
- Do people with HIV infection have a normal life expectancy in the era of combination antiretroviral therapy?BMC medicine · 2013Review
- A new cytokine release assay: a simple approach to monitor the immune status of HIV-infected patients.Infection · 2013Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare the mortality and causes of death in human immunodeficiency syndrome (HIV) patients with the background population.
methodsAll adult HIV patients treated in Danish HIV centers from 1995 to 2008 and 14 controls for each HIV patient were included. Age-adjusted mortality rates (MR) and mortality rate ratios (MRR) were estimated using direct standardization and Poisson regression analyses. Up to four contributory causes of death for each person were included in analyses of cause-specific MR.
resultsA total of 5,137 HIV patients and 71,918 controls were followed for 37,838 and 671,339 person-years (PY), respectively. Among non-injection drug use (IDU) HIV patients, the acquired immune deficiency syndrome (AIDS)-related MR/1,000 PY declined dramatically from 122.9 [95 % confidence interval (CI) 106.8-141.4] in 1995 to 5.0 (95 % CI 3.1-8.1) in 2008. The non-AIDS-related MR did not change substantially from 6.9 (95 % CI 3.8-12.5) to 5.6 (95 % CI 3.6-8.8). The MR of unnatural causes declined from 6.9 (95 % CI 3.8-12.5) to 2.7 (95 % CI 1.4-5.1). The MRR of infections declined from 46.6 (95 % CI 19.6-110.9) to 3.3 (95 % CI 1.6-6.6). The MRR of other natural causes of death remained constant.
conclusionsAfter the introduction of highly active antiretroviral therapy (HAART), the AIDS-related mortality has decreased substantially, but the long-term exposure to HIV and HAART has not translated into increasing mortality from malignancy, cardiovascular, and hepatic diseases.
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