ArticleKidney international2012
APOL1 variants in HIV-associated nephropathy: just one piece of the puzzle.
Article in Kidney international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- APOL1 kidney disease: a critical narrative review of molecular mechanisms, clinical heterogeneity, and the emerging therapeutic landscape.International urology and nephrology · 2026Review
- Pathogenesis of HIV-associated nephropathy in children and adolescents: taking a hard look 40 years later in the era of gene-environment interactions.American journal of physiology. Renal physiology · 2024Review
- Apoprotein L1 risk variants and kidney transplantation: a protocol for systematic review and meta-analysis.The Pan African medical journal · 2022Article
- Risk of End-Stage Renal Disease in HIV-Positive Potential Live Kidney Donors.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2017Article
- Chronic kidney disease in low-income to middle-income countries: the case for increased screening.BMJ global health · 2017Review
- Update on current management of chronic kidney disease in patients with HIV infection.International journal of nephrology and renovascular disease · 2016Review
- APOL1 Risk Variants Are Strongly Associated with HIV-Associated Nephropathy in Black South Africans.Journal of the American Society of Nephrology : JASN · 2015Article
- African origins and chronic kidney disease susceptibility in the human immunodeficiency virus era.World journal of nephrology · 2015Review
- Gene-gene and gene-environment interactions in apolipoprotein L1 gene-associated nephropathy.Clinical journal of the American Society of Nephrology : CJASN · 2014Review
- APOL1 and nephropathy progression in populations of African ancestry.Seminars in nephrology · 2013Review
Corrections and comments
- Comment on
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Considerable attention has been focused on how the APOL1/MYH9 locus determines susceptibility to focal segmental glomerulosclerosis, including HIV-associated nephropathy (HIVAN). Atta and colleagues found that homozygosity for APOL1 risk alleles was associated with many, but not all, HIVAN cases, and that APOL1 variation failed to predict characteristics of disease. Their work gives important impetus to identify other genetic and environmental factors that may provide a 'second hit' linking HIV infection to HIVAN.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.