ArticleEuropean journal of clinical pharmacology2013
Prescription drug dispensing profiles for one million children: a population-based analysis.
Article in European journal of clinical pharmacology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pediatric Outpatient Prescriptions in Countries With Advanced Economies in the 21st Century: A Systematic Review.JAMA network open · 2022Pooled it
- Pooled it
- Knowledge, attitude, and practice toward azithromycin infusion reactions among pediatric nurses: a cross-sectional study.BMC nursing · 2025Article
- Prescription drug use in Danish children and adolescents 2005-2023.European journal of epidemiology · 2025Article
- From Prescription Drugs to Natural Health Products: Medication Use in Canadian Infants.Children (Basel, Switzerland) · 2022Article
- Medicine and supplement use in infants, children, and adolescents depends on sex, age, and socioeconomic status: results of a German longitudinal population-based cohort study (LIFE Child).European journal of pediatrics · 2022Article
- Disruptive Behaviors and Intellectual Disability: Creating a New Script.Frontiers in psychiatry · 2022Article
- Understanding patient characteristics and medication prescriptions in children with mental health and neurodevelopmental disorders referred to a sleep clinic-A quality improvement/quality assurance analysis.Frontiers in psychiatry · 2022Article
- Analysis of the potential inappropriate use of medications in pediatric outpatients in China.BMC health services research · 2021Article
- Paediatric outpatient prescriptions in France between 2010 and 2019: A nationwide population-based study: Paediatric outpatient prescriptions in France, 2010 to 2019.The Lancet regional health. Europe · 2021Article
- Prescription medication use among Canadian children and youth, 2012 to 2017.Health reports · 2021Article
- Application of antibiotics before 3 years of age increases the risk of childhood overweight and obesity.Experimental and therapeutic medicine · 2021Article
- Antibiotic-induced dysbiosis of gut microbiota impairs corneal development in postnatal mice by affecting CCR2 negative macrophage distribution.Mucosal immunology · 2020Article
- Trends in Outpatient Prescription Medicine Use in New Zealand Children 2010-2015: A National Population-Based Study.Paediatric drugs · 2018Article
- Early microbiota, antibiotics and health.Cellular and molecular life sciences : CMLS · 2018Review
- Association of Repeated Intravitreous Bevacizumab Injections With Risk for Glaucoma Surgery.JAMA ophthalmology · 2017Article
- Stochastic Signatures of Involuntary Head Micro-movements Can Be Used to Classify Females of ABIDE into Different Subtypes of Neurodevelopmental Disorders.Frontiers in integrative neuroscience · 2017Article
- Antibiotic perturbation of the preterm infant gut microbiome and resistome.Gut microbes · 2016Review
- Ambulatory Care Visits to Pediatricians in Taiwan: A Nationwide Analysis.International journal of environmental research and public health · 2015Article
- Antibiotics and the developing infant gut microbiota and resistome.Current opinion in microbiology · 2015Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPopulation-based drug utilization databases that comprehensively capture an entire population's drug dispensing are scarce resources for epidemiological studies. This study aimed to examine the prescription-dispensing rates in children in British Columbia (BC) and describe the differences in the dispensing of medications in BC versus children in the United States (US) and Europe.
methodsThe study population was children aged 0-17 years in BC (n = 855,541). Children with at least one prescription dispensed in 2007 were identified using the provincial outpatient prescription dispensing database. All prescriptions were grouped on the basis of the Anatomical Therapeutic Chemical (ATC) classification system. Prevalence of drug dispensing was calculated in each age group, gender, and therapeutic class.
resultsFifty-five percent of BC children were dispensed at least one prescription in 2007. Antibacterials for systemic use, dermatological corticosteroids, and drugs for obstructive airway diseases were commonly dispensed in each age group. The percentage of children who received psychoanaleptics was two to five times higher than rates reported in European countries, but 30% lower than rates reported in the US.
conclusionsHalf of the BC population <18 years received at least one prescription in 2007. Significant variations in drug dispensing were highlighted between BC, the US, and Europe. Future studies are needed to examine the outcomes of the prescribing in terms of benefit and harm. A variety of factors (e.g., disease prevalence rates, drug prescribing preferences) are likely to contribute to disparate dispensing of specific drug classes and should be principal factors in the investigation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.