Evidence map›Paper›PMID 22790252›Full record

ReviewAJNR. American journal of neuroradiology2013

CNS-immune reconstitution inflammatory syndrome in the setting of HIV infection, part 2: discussion of neuro-immune reconstitution inflammatory syndrome with and without other pathogens.

M J D Post, M M Thurnher, D B Clifford, A Nath, R G Gonzalez, R K Gupta, K K Post

Open access · bronzeAbstract readReview
In one paragraph

Review in AJNR. American journal of neuroradiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 52 citations in OpenAlex.

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  14. Drug induced increases in CNS dopamine alter monocyte, macrophage and T cell functions: implications for HAND.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2013
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

M J D PostSection of Neuroradiology, Department of Radiology, University of Miami Miller School of Medicine, Jackson Memorial Medical Center, Miami, FL 33136, USA. jpost@med.miami.edu
M M Thurnher
D B Clifford
A Nath
R G Gonzalez
R K Gupta
K K Post
Harvard University · USJackson Memorial Hospital · USNational Institutes of Health · USSanjay Gandhi Post Graduate Institute of Medical Sciences · INUniversity of Vienna · ATWashington University in St. Louis · US

Funding

Neuropathogenesis of Retroviral InfectionsZIANS003130 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI NATH, AVINDRA · 2011 to 2025
$73.7M
Intramural NIH HHS ZIA NS003130
6 · The paper itself

Abstract

summaryWhile the previous review of CNS-IRIS in the HIV-infected patient on highly active antiretroviral therapy (Part 1) dealt with an overview of the biology, pathology, and neurologic presentation of this condition and a discussion of the atypical imaging findings in PML-IRIS and cryptococcal meningitis-IRIS due to the robust inflammatory response, the current review (Part 2) discusses the imaging findings in other commonly encountered organisms seen in association with CNS-IRIS, namely, VZV, CMV, HIV, Candida organisms, Mycobacterium tuberculosis, and Toxoplasma gondii. Also described is the imaging appearance of CNS-IRIS when not associated with a particular organism. Recognition of these imaging findings will give credence to the diagnosis of CNS-IRIS and will allow the clinician to institute changes in medical management, if necessary, so that immune reconstitution and improved patient outcome can occur with time.

Indexed as

Antiretroviral Therapy, Highly ActiveAIDS-Related Opportunistic InfectionsCandidiasisCentral Nervous System DiseasesCentral Nervous System Fungal InfectionsCentral Nervous System InfectionsCentral Nervous System Viral DiseasesHerpesviridae InfectionsHIV InfectionsHumansImmune Reconstitution Inflammatory SyndromeToxoplasmosis, CerebralTuberculosis, Central Nervous System

Identifiers

PMID22790252
PMCPMC4905746
OpenAlexW2045740223

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.