ArticleCurrent biology : CB2012
Cancer and inflammation: an aspirin a day keeps the cancer at bay.
Article in Current biology : CB, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation.Cell death & disease · 2021Article
- A novel zebrafish intestinal tumor model reveals a role forDisease models & mechanisms · 2018Article
- A Carrier-Free Nanostructure Based on Platinum(IV) Prodrug Enhances Cellular Uptake and Cytotoxicity.Molecular pharmaceutics · 2018Article
- Advances in genomics of bony fish.Briefings in functional genomics · 2014Review
- Systems biology of cancer: entropy, disorder, and selection-driven evolution to independence, invasion and "swarm intelligence".Cancer metastasis reviews · 2013Review
- Aspirin and its related non-steroidal anti-inflammatory drugs.The Libyan journal of medicine · 2013Article
- Obesity-driven inflammation and cancer risk: role of myeloid derived suppressor cells and alternately activated macrophages.American journal of cancer research · 2013Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Live imaging of the interactions between oncogene-transformed cells and leukocytes in zebrafish reveals that PGE(2) promotes the survival and proliferation of cancer cells. Non-steroid anti-inflammatory drugs, like aspirin, are the effective inhibitors of PGE(2) production and could be used with other anti-tumor agents in the treatment of cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.