Evidence map›Paper›PMID 22786999›Full record

ArticleRadiographics : a review publication of the Radiological Society of North America, Inc

State-of-the-art PET/CT of the pancreas: current role and emerging indications.

Dushyant V Sahani, Pietro A Bonaffini, Onofrio A Catalano, Alexander R Guimaraes, Michael A Blake

Open access · greenAbstract read
In one paragraph

Article in Radiographics : a review publication of the Radiological Society of North America, Inc. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 110 citations in OpenAlex.

  1. Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Trial
  2. Head to head comparison of [EJNMMI research · 2026
    Article
  3. Article
  4. Article
  5. Preoperative assessment of pancreatic cancer with [European journal of nuclear medicine and molecular imaging · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Clinical application of AlCancer imaging : the official publication of the International Cancer Imaging Society · 2023
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Positron emission tomography and computed tomography with [European journal of nuclear medicine and molecular imaging · 2022
    Article
  17. Review
  18. Article
  19. Advanced imaging techniques for chronic pancreatitis.Abdominal radiology (New York) · 2020
    Review
  20. Molecular imaging of a glucagonoma withRadiology case reports · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Dushyant V SahaniDepartment of Radiology, Division of Abdominal Imaging and Interventional Radiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, White 270, Boston, MA 02114, USA. dsahani@partners.org
Pietro A Bonaffini
Onofrio A Catalano
Alexander R Guimaraes
Michael A Blake
Harvard University Press · USMassachusetts General Hospital · USSDN Istituto di Ricerca Diagnostica e Nucleare · ITUniversity of Milano-Bicocca · IT

Funding

Validation of MRI Microvascular Biomarkers in Pancreatic Cancer with Magnetic NanoparticlesK08EB012859 · NIBIB · OREGON HEALTH & SCIENCE UNIVERSITY · PI GUIMARAES, ALEXANDER SAVIO RAMOS · 2011 to 2015
$875k
NIBIB NIH HHS K08 EB012859
6 · The paper itself

Abstract

Fused positron emission tomography (PET)/computed tomography (CT) is a recently developed technology that couples the functional information of PET with the anatomic details of CT. Integrated PET/CT scanners produce both PET and contrast material-enhanced CT images of the entire body in one setting. Typically, the amount of fluorine 18 (18F) fluorodeoxyglucose (FDG) uptake in normal pancreatic parenchyma is insignificant compared with that of the liver. However, both malignant (eg, adenocarcinoma) and benign (eg, acute pancreatitis) pancreatic conditions may demonstrate intense FDG uptake. PET/CT provides an opportunity to depict pancreatic tumors and distant metastases, perform preoperative staging, and monitor response to treatment, and it has proved useful in distinguishing postoperative fibrosis from recurrence. In selected cases, PET/CT findings may be used to help diagnose autoimmune pancreatitis mimicking a mass by depicting systemic involvement. PET/CT may also be used to direct biopsy to sites more likely to yield representative tumor tissue. Novel radiolabeled molecules, such as sigma-receptor ligands and 18F-3'-fluoro-3'-deoxy-l-thymidine (FLT), may play an even greater role in distinguishing tumor recurrence from postoperative fibrosis or inflammation.

Indexed as

Positron-Emission TomographyTomography, X-Ray ComputedHumansImage EnhancementMultimodal ImagingPancreasPancreatic Diseases

Identifiers

PMID22786999
PMCPMC6939848
OpenAlexW2123535174

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.