ArticlePlant physiology2012
Arabidopsis ETHE1 encodes a sulfur dioxygenase that is essential for embryo and endosperm development.
Article in Plant physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 68 citations in OpenAlex.
- Molecular Cloning, In Silico Characterization, and Promoter Analysis of a PutativeCurrent issues in molecular biology · 2026Article
- Protein persulfidation: a ubiquitous modification regulating a broad spectrum of biological processes.Journal of experimental botany · 2026Review
- Transcriptome analysis reveals the mechanism and key role of CdPER47 in bermudagrass (Cynodon dactylon) adaptation to submergence and post-submergence stresses.BMC plant biology · 2026Article
- Self-bioRxiv : the preprint server for biology · 2026Article
- Structure and function of persulfide dioxygenase fromiScience · 2026Article
- Targeting ETHE1 inhibits tumorigenesisOncology letters · 2025Article
- Bioremediation of non-point hydrogen sulfide emissions using bacterial cellulose/activated carbon membrane.Microbial cell factories · 2025Article
- Article
- Glyoxalase 2: Towards a Broader View of the Second Player of the Glyoxalase System.Antioxidants (Basel, Switzerland) · 2022Review
- Genome-wide analysis of sulfur-encoding biosynthetic genes in rice (Oryza sativa L.) with Arabidopsis as the sulfur-dependent model plant.Scientific reports · 2022Article
- Dynamic changes in primexine during the tetrad stage of pollen development.Plant physiology · 2021Article
- Defense responses of sulfur dioxygenase to sulfide stress in the razor clam Sinonovacula constricta.Genes & genomics · 2021Article
- The Resistance of Oilseed Rape Microspore-Derived Embryos to Osmotic Stress Is Associated With the Accumulation of Energy Metabolism Proteins, Redox Homeostasis, Higher Abscisic Acid, and Cytokinin Contents.Frontiers in plant science · 2021Article
- From methylglyoxal to pyruvate: a genome-wide study for the identification of glyoxalases and D-lactate dehydrogenases in Sorghum bicolor.BMC genomics · 2020Article
- Heat Shock Responsive Gene Expression Modulated by mRNA Poly(A) Tail Length.Frontiers in plant science · 2020Article
- ETHE1 overexpression promotes SIRT1 and PGC1α mediated aerobic glycolysis, oxidative phosphorylation, mitochondrial biogenesis and colorectal cancer.Oncotarget · 2019Article
- Article
- Enhanced Formation of Methylglyoxal-Derived Advanced Glycation End Products inFrontiers in plant science · 2018Article
- Sulfur Oxidation in the Acidophilic AutotrophicFrontiers in microbiology · 2018Review
- The Role of Persulfide Metabolism During Arabidopsis Seed Development Under Light and Dark Conditions.Frontiers in plant science · 2018Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Mutations in human (Homo sapiens) ETHYLMALONIC ENCEPHALOPATHY PROTEIN1 (ETHE1) result in the complex metabolic disease ethylmalonic encephalopathy, which is characterized in part by brain lesions, lactic acidemia, excretion of ethylmalonic acid, and ultimately death. ETHE1-like genes are found in a wide range of organisms; however, the biochemical and physiological role(s) of ETHE1 have not been examined outside the context of ethylmalonic encephalopathy. In this study we characterized Arabidopsis (Arabidopsis thaliana) ETHE1 and determined the effect of an ETHE1 loss-of-function mutation to investigate the role(s) of ETHE1 in plants. Arabidopsis ETHE1 is localized in the mitochondrion and exhibits sulfur dioxygenase activity. Seeds homozygous for a DNA insertion in ETHE1 exhibit alterations in endosperm development that are accompanied by a delay in embryo development followed by embryo arrest by early heart stage. Strong ETHE1 labeling was observed in the peripheral and chalazal endosperm of wild-type seeds prior to cellularization. Therefore, ETHE1 appears to play an essential role in regulating sulfide levels in seeds.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.