Evidence map›Paper›PMID 22785185›Full record

ArticleJournal of clinical microbiology2012

Diversity of the Cronobacter genus as revealed by multilocus sequence typing.

S Joseph, H Sonbol, S Hariri, P Desai, M McClelland, S J Forsythe

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed.

  1. Probing Genomic Diversity ofFoods (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Characterization ofFrontiers in microbiology · 2025
    Article
  4. Article
  5. Article
  6. Identification, Typing and Drug Resistance ofFoods (Basel, Switzerland) · 2023
    Article
  7. Article
  8. Characterization ofMicroorganisms · 2022
    Article
  9. Frontiers in microbiology · 2022
    Article
  10. Detection of Genus and Three Important Species ofFrontiers in microbiology · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Analysis of the Molecular Diversity AmongFrontiers in microbiology · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

S JosephPathogen Research Group, School of Science and Technology, Nottingham Trent University, Nottingham, United Kingdom.
H Sonbol
S Hariri
P Desai
M McClelland
S J Forsythe

Funding

Comparative Genomics in the EnterobateriaceaeR01AI052237 · NIAID · WASHINGTON UNIVERSITY · PI WEINSTOCK, GEORGE M · 2002 to 2009
$4.1M
Identification of Salmonella Genes Important for Systemic ColonizationR01AI083646 · NIAID · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ANDREWS-POLYMENIS, HELENE L · 2009 to 2012
$1.6M
Salmonella Genes Associated with Colonization of Specific HostsR01AI075093 · NIAID · VACCINE RESEARCH INSTITUTE OF SAN DIEGO · PI MCCLELLAND, MICHAEL · 2009 to 2010
$928k
NIAID NIH HHS AI052237NIAID NIH HHS AI075093NIAID NIH HHS AI083646NIAID NIH HHS R01 AI052237NIAID NIH HHS R01 AI075093NIAID NIH HHS R01 AI083646
6 · The paper itself

Abstract

Cronobacter (previously known as Enterobacter sakazakii) is a diverse bacterial genus consisting of seven species: C. sakazakii, C. malonaticus, C. turicensis, C. universalis, C. muytjensii, C. dublinensis, and C. condimenti. In this study, we have used a multilocus sequence typing (MLST) approach employing the alleles of 7 genes (atpD, fusA, glnS, gltB, gyrB, infB, and ppsA; total length, 3,036 bp) to investigate the phylogenetic relationship of 325 Cronobacter species isolates. Strains were chosen on the basis of their species, geographic and temporal distribution, source, and clinical outcome. The earliest strain was isolated from milk powder in 1950, and the earliest clinical strain was isolated in 1953. The existence of seven species was supported by MLST. Intraspecific variation ranged from low diversity in C. sakazakii to extensive diversity within some species, such as C. muytjensii and C. dublinensis, including evidence of gene conversion between species. The predominant species from clinical sources was found to be C. sakazakii. C. sakazakii sequence type 4 (ST4) was the predominant sequence type of cerebral spinal fluid isolates from cases of meningitis.

Indexed as

PhylogenyBacterial ProteinsCluster AnalysisCronobacterGenetic VariationGram-Negative Bacterial InfectionsHumansMultilocus Sequence TypingSequence Homology, Nucleic AcidBacterial Proteins

Identifiers

PMID22785185
PMCPMC3421776

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.