Evidence map›Paper›PMID 22784461›Full record

ArticleTwin research and human genetics : the official journal of the International Society for Twin Studies2012

Multiple regression analysis of reading performance data from twin pairs with reading difficulties and nontwin siblings: the augmented model.

Sally J Wadsworth, Richard K Olson, Erik G Willcutt, John C DeFries

Abstract read
In one paragraph

Article in Twin research and human genetics : the official journal of the International Society for Twin Studies, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sally J WadsworthInstitute for Behavioral Genetics, University of Colorado, Boulder, CO 80309, USA. Sally.Wadsworth@Colorado.edu
Richard K Olson
Erik G Willcutt
John C DeFries

Funding

VALIDITY OF SUBTYPES OF ADHDP50HD027802 · NICHD · UNIVERSITY OF COLORADO AT BOULDER · PI ERIK G WILLCUTT · 1990 to 2026
$44.9M
NICHD NIH HHS HD027802NICHD NIH HHS P50 HD027802
6 · The paper itself

Abstract

The augmented multiple regression model for the analysis of data from selected twin pairs was extended to facilitate analyses of data from twin pairs and nontwin siblings. Fitting this extended model to data from both selected twin pairs and siblings yields direct estimates of heritability (h2) and the difference between environmental influences shared by members of twin pairs and those of sib or twin-sib pairs (i.e., c2(t) - c2 (s)). When this model was fitted to reading performance data from 293 monozygotic and 436 dizygotic pairs selected for reading difficulties, and 291 of their nontwin siblings, h2 = .48 ± .22, p = .03, and c2 (t) - c2 (s) = .22 ± .12, p = .06. Although the test for differential shared environmental influences is only marginally significant, the results of this analysis suggest that environmental influences on reading performance that are shared by members of twin pairs (.36) may be substantially greater than those for less contemporaneous twin-sibling pairs (.14).

Indexed as

Models, TheoreticalReadingAdolescentColoradoFemaleHumansMaleRegression AnalysisSiblingsTwins, DizygoticTwins, MonozygoticYoung Adult

Identifiers

PMID22784461
PMCPMC3398740

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.