ArticleBMC veterinary research2012
Distribution of extrahepatic congenital portosystemic shunt morphology in predisposed dog breeds.
Article in BMC veterinary research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Incidence of portosystemic shunts in Finnish miniature schnauzer litters.Acta veterinaria Scandinavica · 2026Article
- Surgical treatment of concomitant congenital left gastro-azygos and extrahepatic umbilico-caval portosystemic shunts in a dog.The Canadian veterinary journal = La revue veterinaire canadienne · 2025Article
- A Window Opens and a Shunt Closes: A New Laparoscopic Approach for the Attenuation of the Gastrophrenic Shunt.Veterinary sciences · 2025Article
- Single Posthepatic Portosystemic Shunt Communicated With Internal Thoracic Vein and Azygos Continuation of the Caudal Vena Cava in a Dog.Veterinary medicine and science · 2024Article
- Prediction of outcome after ligation or thin film banding of extrahepatic shunts, based on plasma albumin concentration and hematologic expression of 8 target genes in 85 dogs.Journal of veterinary internal medicine · 2023Article
- Anomalies of the Portal Venous System in Dogs and Cats as Seen on Multidetector-Row Computed Tomography: An Overview and Systematization Proposal.Veterinary sciences · 2019Review
- Genome-wide based model predicting recovery from portosystemic shunting after liver shunt attenuation in dogs.Journal of veterinary internal medicine · 2018Article
- Urethral plugs in dogs.Journal of veterinary internal medicineArticle
- Comparison of Serum Bile Acid Concentrations Between Maltese and Other Breeds of Dogs With Portosystemic Shunt.In vivo (Athens, Greece)Article
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAn inherited basis for congenital extrahepatic portosystemic shunts (EHPSS) has been demonstrated in several small dog breeds. If in general both portocaval and porto-azygous shunts occur in breeds predisposed to portosystemic shunts then this could indicate a common genetic background. This study was performed to determine the distribution of extrahepatic portocaval and porto-azygous shunts in purebred dog populations.
resultsData of 135 client owned dogs diagnosed with EHPSS at the Faculty of Veterinary Medicine of Utrecht University from 2001 - 2010 were retrospectively analyzed. The correlation between shunt localization, sex, age, dog size and breed were studied. The study group consisted of 54 males and 81 females from 24 breeds. Twenty-five percent of dogs had porto-azygous shunts and 75% had portocaval shunts. Of the dogs with porto-azygous shunts only 27% was male (P = 0.006). No significant sex difference was detected in dogs with a portocaval shunt. Both phenotypes were present in almost all breeds represented with more than six cases. Small dogs are mostly diagnosed with portocaval shunts (79%) whereas both types are detected. The age at diagnosis in dogs with porto-azygous shunts was significantly higher than that of dogs with portocaval shunts (P < 0.001).
conclusionThe remarkable similarity of phenotypic variation in many dog breeds may indicate common underlying genes responsible for EHPSS across breeds. The subtype of EHPSS could be determined by a minor genetic component or modulating factors during embryonic development.
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