Evidence map›Paper›PMID 22784213›Full record

ArticleMaternal & child nutrition2014

Comparison of mid-infrared transmission spectroscopy with biochemical methods for the determination of macronutrients in human milk.

Dolores Silvestre, Miriam Fraga, María Gormaz, Ester Torres, Máximo Vento

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Maternal & child nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Comparison of macronutrient content in human milk measured by mid-infrared human milk analyzer and reference methods.Journal of perinatology : official journal of the California Perinatal Association · 2019
    Article
  10. Transmission infrared spectroscopy for rapid quantification of fat, protein, and lactose concentrations in human milk.Journal of perinatology : official journal of the California Perinatal Association · 2018
    Article
  11. Review
  12. Validation of mid-infrared spectroscopy for macronutrient analysis of human milk.Journal of perinatology : official journal of the California Perinatal Association · 2017
    Article
  13. Assessment of human milk composition using mid-infrared analyzers requires calibration adjustment.Journal of perinatology : official journal of the California Perinatal Association · 2017
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Dolores SilvestreDepartment of Pharmacy, University CEU Cardenal Herrera, Moncada, Valencia, Spain Division of Neonatology, University and Polytechnic Hospital La Fe, Valencia, Spain Health Research Institute La Fe, Valencia, Spain.
Miriam Fraga
María Gormaz
Ester Torres
Máximo Vento
Hospital Universitari i Politècnic La Fe · ESLeitat Technological Center · ESUniversidad Cardenal Herrera CEU · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The variability of human milk (HM) composition renders analysis of its components essential for optimal nutrition of preterm fed either with donor's or own mother's milk. To fulfil this requirement, various analytical instruments have been subjected to scientific and clinical evaluation. The objective of this study was to evaluate the suitability of a rapid method for the analysis of macronutrients in HM as compared with the analytical methods applied by cow's milk industry. Mature milk from 39 donors was analysed using an infrared human milk analyser (HMA) and compared with biochemical reference laboratory methods. The statistical analysis was based on the use of paired data tests. The use of an infrared HMA for the analysis of lipids, proteins and lactose in HM proved satisfactory as regards the rapidity, simplicity and the required sample volume. The instrument afforded good linearity and precision in application to all three nutrients. However, accuracy was not acceptable when compared with the reference methods, with overestimation of the lipid content and underestimation of the amount of proteins and lactose contents. The use of mid-infrared HMA might become the standard for rapid analysis of HM once standardisation and rigorous and systematic calibration is provided.

Indexed as

Chemistry Techniques, AnalyticalDietary FatsDietary ProteinsFemaleHumansLactoseMilk, HumanSpectrophotometry, InfraredDietary FatsDietary ProteinsLactosefortificationhuman milkmacronutrientsmilk analysersmilk bankingquantitative methods

Identifiers

PMID22784213
PMCPMC6860261
OpenAlexW1777490031

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.