ArticleFrontiers in pharmacology2012
Brain-Gut Interactions in IBS.
Article in Frontiers in pharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05083091 (Smartphone Stress Management Training for Irritable Bowel Syndrome), which is not on this map. Cited by 59 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Smartphone Stress Management Training for Irritable Bowel Syndrome
Who cites it
59 citing papers in PubMed, 1 synthesis or guideline pooled it.
- [A Meta-Analysis on the Effects of Mind-Body Therapy on Patients with Irritable Bowel Syndrome].Journal of Korean Academy of Nursing · 2020Pooled it
- Short intense psychological stress induced by skydiving does not impair intestinal barrier function.PloS one · 2021Trial
- Neuroglobin: A New Player in the Gut-Brain Axis.International journal of molecular sciences · 2026Review
- Pathophysiological and Therapeutic Association between Brain-Gut Axis and Irritable Bowel Syndrome: A Systematic Review.Pakistan journal of medical sciences · 2026Review
- Symptom Severity, Body Image Dissatisfaction, and Movement Behaviors in Irritable Bowel Syndrome: Analysis of Quality of Life Determinants.Healthcare (Basel, Switzerland) · 2026Article
- Physical Activity and Irritable Bowel Syndrome: The Role of Evolutionary Mismatch in Chronic Disease Risk.American journal of biological anthropology · 2025Article
- Mediating Role of Negative Affectivity in the Association Between Lifetime Trauma and Gastrointestinal Symptoms.Healthcare (Basel, Switzerland) · 2025Article
- Patients with Irritable Bowel Syndrome Exhibit Aberrant Expression of Endogenous Retroviruses and SETDB1.Cells · 2025Article
- Bibliometric analysis of the 100 most-cited papers about the role of gut microbiota in irritable bowel syndrome from 2000 to 2021.Clinical and experimental medicine · 2023Article
- Best Parameters of Heart Rate Variability for Assessing Autonomic Responses to Brief Rectal Distention in Patients with Irritable Bowel Syndrome.Sensors (Basel, Switzerland) · 2023Article
- Irritable Bowel Syndrome and the Gut Microbiome: A Comprehensive Review.Journal of clinical medicine · 2023Review
- Psychometric properties of Persian version of irritable bowel syndrome- behavioral responses questionnaire (IBS-BRQ).Gastroenterology and hepatology from bed to bench · 2023Article
- Psychobiotics: the Influence of Gut Microbiota on the Gut-Brain Axis in Neurological Disorders.Journal of molecular neuroscience : MN · 2022Article
- Article
- Factors related to irritable bowel syndrome and differences among subtypes: A cross-sectional study in the UK Biobank.Frontiers in pharmacology · 2022Article
- Tapping into 5-HTInternational journal of molecular sciences · 2021Review
- Sexual dimorphism in maternally separated rats: effects of repeated homotypic stress on gastrointestinal motor functions.Experimental brain research · 2021Article
- Uncovering the pathophysiology of irritable bowel syndrome by exploring the gut-brain axis: a narrative review.Annals of translational medicine · 2021Review
- Inflammation and Overlap of Irritable Bowel Syndrome and Functional Dyspepsia.Journal of neurogastroenterology and motility · 2021Review
- Differential Regulation of Human Serotonin Receptor Type 3A by Chanoclavine and Ergonovine.Molecules (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Irritable bowel syndrome (IBS) is a common gastrointestinal disorder with an estimated prevalence of 10-20%. Current understanding of the pathophysiology of IBS is incomplete due to the lack of a clearly identified pathological abnormality and due to the lack of reliable biomarkers. Possible mechanisms believed to contribute to IBS development and IBS like symptoms include physical stressors, such as infection or inflammation, psychological, and environmental factors, like anxiety, depression, and significant negative life events. Some of these mechanisms may involve the brain-gut axis (BGA). In this article we review the current knowledge on the possible involvement of the BGA in IBS and discuss new directions for potential future therapies of IBS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.