Evidence map›Paper›PMID 22783162›Full record

ArticleFrontiers in neuroscience2012

Decision points: the factors influencing the decision to feed in the medicinal leech.

Quentin Gaudry, William B Kristan

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Circuit-constrained molecular neuroethology in the medicinal leech Hirudo verbana.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026
    Review
  2. Article
  3. Article
  4. Feeding, hunger, satiety and serotonin in invertebrates.Proceedings. Biological sciences · 2020
    Article
  5. Enhancement of habituation during escape swimming in starved crayfish.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2018
    Article
  6. Satiation level affects anti-predatory decisions in foraging juvenile crayfish.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2017
    Article
  7. Article
  8. Article
  9. Article
  10. Which way is up? Asymmetric spectral input along the dorsal-ventral axis influences postural responses in an amphibious annelid.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2014
    Article
  11. Habituation, sensitization, and Pavlovian conditioning.Frontiers in integrative neuroscience · 2014
    Article
  12. Invertebrate behavior-actions or responses?Frontiers in neuroscience · 2013
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Quentin GaudryDepartment of Neurobiology, Harvard Medical School Boston, MA, USA.
William B Kristan

Funding

NEUROSCIENCES CONTROL OF INTERACTIONS AMONG BEHAVIORSR01MH043396 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KRISTAN, WILLIAM B · 1988 to 2013
$3.9M
NIMH NIH HHS R01 MH043396
6 · The paper itself

Abstract

The decision to feed is a complex task that requires making several small independent choices. Am I hungry? Where do I look for food? Is there something better I'd rather be doing? When should I stop? With all of these questions, it is no wonder that decisions about feeding depend on several sensory modalities and that the influences of these sensory systems would be evident throughout the nervous system. The leech is uniquely well suited for studying these complicated questions due to its relatively simple nervous system, its exceptionally well-characterized behaviors and neural circuits, and the ease with which one can employ semi-intact preparations to study the link between physiology and decision-making. We will begin this review by discussing the cellular substrates that govern the decision to initiate and to terminate a bout of feeding. We will then discuss how feeding temporarily blocks competing behaviors from being expressed while the animal continues to feed. Then we will review what is currently known about how feeding affects long-term behavioral choices of the leech. Finally, we conclude with a short discussion of the advantages of the leech's decision-making circuit's design and how this design might be applicable to all decision circuits.

Indexed as

behavioral choicedecision-makingdistributedfeedingleechmodularsensory gatingserotonin

Identifiers

PMID22783162
PMCPMC3390556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.