Evidence map›Paper›PMID 22782568›Full record

Trial reportEuropean radiology2013

Detection of coronary plaques using MR coronary vessel wall imaging: validation of findings with intravascular ultrasound.

Suzanne Gerretsen, Alfons G Kessels, Patty J Nelemans, Jouke Dijkstra, Johan H C Reiber, Rob J van der Geest, Marcus Katoh, Johannes Waltenberger, Jos M A van Engelshoven, Rene M Botnar and 2 more

Abstract readClinical TrialValidation Study
PubMed Publisher
In one paragraph

Trial report in European radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. SCMR Position Paper (2020) on clinical indications for cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2020
    Guideline
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Noninvasive diagnosis of vulnerable coronary plaque.World journal of cardiology · 2016
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Suzanne GerretsenDepartment of Radiology, Maastricht University Medical Centre, P. Debyelaan 25, 6229HX, Maastricht, The Netherlands.
Alfons G Kessels
Patty J Nelemans
Jouke Dijkstra
Johan H C Reiber
Rob J van der Geest
Marcus Katoh
Johannes Waltenberger
Jos M A van Engelshoven
Rene M Botnar
M Eline Kooi
Tim Leiner
Leiden University · NLMaastricht University Medical Centre · NLMaastricht University · NLHelios Klinikum Krefeld · DEKing's College London · GBUniversity of Münster · DEUtrecht University · NL

Funding

British Heart Foundation RG/12/1/29262
6 · The paper itself

Abstract

objectivesCompared with X-ray coronary angiography (CAG), magnetic resonance imaging of the coronary vessel wall (MR-CVW) may provide more information about plaque burden and coronary remodelling. We compared MR-CVW with intravascular ultrasound (IVUS), the standard of reference for coronary vessel wall imaging, with regard to plaque detection and wall thickness measurements.

methodsIn this study 17 patients with chest pain, who had been referred for CAG, were included. Patients underwent IVUS and MR-CVW imaging of the right coronary artery (RCA). Subsequently, the coronary vessel wall was analysed for the presence and location of coronary plaques.

resultsFifty-two matching RCA regions of interest were available for comparison. There was good agreement between IVUS and MR-CVW for qualitative assessment of presence of disease, with a sensitivity of 94% and specificity of 76%. Wall thickness measurements demonstrated a significant difference between mean wall thickness on IVUS and MR-CVW (0.48 vs 1.24 mm, P < 0.001), but great heterogeneity between wall thickness measurements, resulting in a low correlation between IVUS and MR-CVW.

conclusionsMR-CVW has high sensitivity for the detection of coronary vessel wall thickening in the RCA compared with IVUS. However, the use of MRI for accurate absolute wall thickness measurements is not supported when a longitudinal acquisition orientation is used.

Indexed as

Magnetic Resonance AngiographyUltrasonography, InterventionalCoronary AngiographyCoronary Artery DiseaseFemaleHumansImage Interpretation, Computer-AssistedLinear ModelsMaleMiddle AgedPercutaneous Coronary InterventionPlaque, AtheroscleroticPredictive Value of TestsROC CurveSensitivity and Specificity

Identifiers

PMID22782568
OpenAlexW1994560237

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.