Evidence map›Paper›PMID 22782018›Full record

ReviewCurrent opinion in gastroenterology2012

Chronic pancreatitis.

Matthew J DiMagno, Eugene P DiMagno

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Advances in the Management of Pain in Chronic Pancreatitis.Current gastroenterology reports · 2023
    Review
  4. Article
  5. Role of angiogenesis in beta-cell epithelial-mesenchymal transition in chronic pancreatitis-induced diabetes.Laboratory investigation; a journal of technical methods and pathology · 2022
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Genetics of pancreatitis with a focus on the pancreatic ducts.Minerva gastroenterologica e dietologica · 2012
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Matthew J DiMagnoDivision of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109-0682, USA. mdimagno@umich.edu
Eugene P DiMagno
Mayo Clinic · USMichigan Medicine · US

Funding

Inflammatory response to pancreatitis in CF mice: sodium & impaired apoptosisK08DK073298 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DIMAGNO, MATTHEW J · 2006 to 2010
$716k
Pioglitazone Therapy for Endocrine and Exocrine Disease in Alcoholic PancreatitisR21AA017271 · NIAAA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DIMAGNO, MATTHEW J · 2008 to 2009
$406k
NIAAA NIH HHS R21 AA017271NIDDK NIH HHS K08 DK073298
6 · The paper itself

Abstract

purpose of reviewWe review important new clinical observations in chronic pancreatitis reported in 2011. RECENT

findingsSmoking increases the risk of nongallstone acute pancreatitis and the progression of acute pancreatitis to chronic pancreatitis. Binge drinking during Oktoberfest did not associate with increased hospital admissions for acute pancreatitis. The unfolded protein response is an adaptive mechanism to maintain pancreatic health in response to noxious stimuli such as alcohol. Onset of diabetes mellitus in chronic pancreatitis is likely due to progressive disease rather than individual variables. Insufficient pancreatic enzyme dosing is common for treatment of pancreatic steatorrhea; 90 000 United States Pharmacopeia units of lipase should be given with meals. Surgical drainage provides sustained, superior pain relief compared with endoscopic treatment in patients advanced chronic pancreatitis with a dilated main duct ± pancreatic stones. The central acting gabapentoid pregabalin affords a modest 12% pain reduction in patients with chronic pancreatitis but approximately 30% of patients have significant side effects. SUMMARY: Patients with nongallstone-related acute pancreatitis or chronic pancreatitis of any cause should cease smoking. Results of this year's investigations further elucidated the pancreatic pathobiology due to alcohol, onset of diabetes mellitus in chronic pancreatitis, and the mechanisms and treatment of neuropathic pain in chronic pancreatitis.

Indexed as

Pain ManagementAbdominal PainBinge DrinkingDiabetes MellitusDrainageExocrine Pancreatic InsufficiencyHumansPancreatitisPancreatitis, ChronicSmokingUnfolded Protein Response

Identifiers

PMID22782018
PMCPMC3480324
OpenAlexW4252352543

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.