Cell death: multitasking p53 promotes necrosis.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

1. Cardiotoxicity of Anticancer Drugs: Molecular Mechanisms and Strategies for Cardioprotection.Frontiers in cardiovascular medicine · 2022
   Review
2. The sphingosine kinase inhibitor SKI-V suppresses cervical cancer cell growth.International journal of biological sciences · 2022
   Article
3. The Roles of p53 in Mitochondrial Dynamics and Cancer Metabolism: The Pendulum between Survival and Death in Breast Cancer?Cancers · 2018
   Review
4. Transgenerational Sterility of Piwi Mutants Represents a Dynamic Form of Adult Reproductive Diapause.Cell reports · 2018
   Article
5. Activation of Akt by SC79 protects myocardiocytes from oxygen and glucose deprivation (OGD)/re-oxygenation.Oncotarget · 2017
   Article
6. The mechanisms of graphene-based materials-induced programmed cell death: a review of apoptosis, autophagy, and programmed necrosis.International journal of nanomedicine · 2017
   Review
7. The Machado-Joseph Disease Deubiquitinase Ataxin-3 Regulates the Stability and Apoptotic Function of p53.PLoS biology · 2016
   Article
8. Phenotype anchoring in zebrafish reveals a potential role for matrix metalloproteinases (MMPs) in tamoxifen's effects on skin epithelium.Toxicology and applied pharmacology · 2016
   Article
9. Activation of SphK1 by K6PC-5 Inhibits Oxygen-Glucose Deprivation/Reoxygenation-Induced Myocardial Cell Death.DNA and cell biology · 2015
   Article
10. Influence of P53 on the radiotherapy response of hepatocellular carcinoma.Clinical and molecular hepatology · 2015
    Article
11. Regulated cell death in AKI.Journal of the American Society of Nephrology : JASN · 2014
    Review
12. Understanding the non-canonical pathways involved in p53-mediated tumor suppression.Carcinogenesis · 2014
    Article
13. The mitochondrial cyclophilin D/p53 complexation mediates doxorubicin-induced non-apoptotic death of A549 lung cancer cells.Molecular and cellular biochemistry · 2014
    Article
14. Regulated necrosis: the expanding network of non-apoptotic cell death pathways.Nature reviews. Molecular cell biology · 2014
    Review
15. Oxygen glucose deprivation (OGD)/re-oxygenation-induced in vitro neuronal cell death involves mitochondrial cyclophilin-D/P53 signaling axis.Neurochemical research · 2013
    Article

Corrections and comments

• Comment on
  p53 opens the mitochondrial permeability transition pore to trigger necrosis.2012

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.