Evidence map›Paper›PMID 22781903›Full record

ReviewNature reviews. Molecular cell biology2012

Orchestrating vesicle transport, ESCRTs and kinase surveillance during abscission.

Chun-Ting Chen, Heidi Hehnly, Stephen J Doxsey

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Molecular cell biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Cytokinesis During the First Division of a Mouse Embryo.Frontiers in cell and developmental biology · 2021
    Article
  5. Article
  6. TheMicroorganisms · 2019
    Article
  7. Review
  8. Article
  9. Article
  10. Polarized Exocytosis.Cold Spring Harbor perspectives in biology · 2017
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. How PI3K-derived lipids control cell division.Frontiers in cell and developmental biology · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chun-Ting ChenProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.
Heidi Hehnly
Stephen J Doxsey
University of Massachusetts Chan Medical School · US

Funding

Mitotic functions of cilia proteinsR01GM051994 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI DOXSEY, STEPHEN J · 1995 to 2014
$4.3M
Molecular mechanism of exocyst-centriolin complexes in abscissionF32GM095161 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI HEHNLY, HEIDI · 2010 to 2011
$99k
NIGMS NIH HHS F32 GM095161NIGMS NIH HHS R01 GM051994
6 · The paper itself

Abstract

During the final stage of cell division, the future daughter cells are physically separated through abscission. This process requires coordination of many molecular machines, including endocytic and secretory vesicle trafficking proteins as well as ESCRT (endosomal sorting complex required for transport) proteins, that mediate a complex series of events to culminate in the final separation of daughter cells. Abscission is coordinated with other cellular processes (for example, nuclear pore reassembly) through mitotic kinases such as Aurora B and Polo-like kinase 1, which act as master regulators to ensure proper progression of abscission.

Indexed as

Cell Cycle ProteinsProtein Serine-Threonine KinasesProtein TransportProto-Oncogene ProteinsAnimalsAurora KinasesCell DivisionCytokinesisEndosomal Sorting Complexes Required for TransportEndosomesNuclear PorePolo-Like Kinase 1Signal TransductionAurora KinasesCell Cycle ProteinsEndosomal Sorting Complexes Required for TransportPolo-Like Kinase 1Protein Serine-Threonine KinasesProto-Oncogene Proteins

Identifiers

PMID22781903
PMCPMC4215936
OpenAlexW2093846020

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.