ArticleNature biotechnology2012
Gene therapy matures in the clinic.
Article in Nature biotechnology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.Science (New York, N.Y.) · 2013Trial
- Food and Drug Administration Guidance on Design of Clinical Trials for Gene Therapy Products with Potential for Genome Integration or Genome Editing and Associated Long-Term Follow-Up of Research Subjects.Applied biosafety : journal of the American Biological Safety Association · 2022Review
- Enhance transgene responses through improving cellular uptake and intracellular trafficking by bio-inspired non-viral vectors.Journal of nanobiotechnology · 2020Article
- Next-generation muscle-directed gene therapy by in silico vector design.Nature communications · 2019Article
- Developing Modern Pain Therapies.Frontiers in neuroscience · 2019Review
- Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications.Chemical Society reviews · 2018Review
- LentiPro26: novel stable cell lines for constitutive lentiviral vector production.Scientific reports · 2018Article
- Single-step cloning-screening method: a new tool for developing and studying high-titer viral vector producer cells.Gene therapy · 2015Article
- Genome-wide computational analysis reveals cardiomyocyte-specific transcriptional Cis-regulatory motifs that enable efficient cardiac gene therapy.Molecular therapy : the journal of the American Society of Gene Therapy · 2015Article
- CD133-targeted gene transfer into long-term repopulating hematopoietic stem cells.Molecular therapy : the journal of the American Society of Gene Therapy · 2015Article
- Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy.Journal of controlled release : official journal of the Controlled Release Society · 2014Article
- Article
- Liver-specific transcriptional modules identified by genome-wide in silico analysis enable efficient gene therapy in mice and non-human primates.Molecular therapy : the journal of the American Society of Gene Therapy · 2014Article
- On the possible involvement of bovine serum albumin precursor in lipofection pathway.Journal of biosciences · 2014Article
- Clinical applications involving CNS gene transfer.Advances in genetics · 2014Review
- Preclinical safety and efficacy of an anti-HIV-1 lentiviral vector containing a short hairpin RNA to CCR5 and the C46 fusion inhibitor.Molecular therapy. Methods & clinical development · 2014Article
- Article
- Review
- Review
- From bench to bedside: preclinical evaluation of a self-inactivating gammaretroviral vector for the gene therapy of X-linked chronic granulomatous disease.Human gene therapy. Clinical development · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
22781675What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.