ArticleBMC plant biology2012
Clustered metallothionein genes are co-regulated in rice and ectopic expression of OsMT1e-P confers multiple abiotic stress tolerance in tobacco via ROS scavenging.
Article in BMC plant biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
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Who cites it
58 citing papers in PubMed, 150 citations in OpenAlex.
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- Heat-stress-induced ROS in maize silks cause late pollen tube growth arrest and sterility.iScience · 2024Article
- Regulation of nitro-oxidative homeostasis: an effective approach to enhance salinity tolerance in plants.Plant cell reports · 2024Review
- Physiological and Proteome Analysis of the Effects of Chitosan Oligosaccharides on Salt Tolerance of Rice Seedlings.International journal of molecular sciences · 2024Article
- Metallothionein family genes in kiwifruit: characterization and determining their roles in plant's response to different stresses.Frontiers in plant science · 2024Article
- Where the wild things are: genetic associations of environmental adaptation in the Oryza rufipogon species complex.G3 (Bethesda, Md.) · 2023Article
- DNA methylation dynamics in a coastal foundation seagrass species under abiotic stressors.Proceedings. Biological sciences · 2023Article
- Transgenic tobacco co-expressing flavodoxin and betaine aldehyde dehydrogenase confers cadmium tolerance through boosting antioxidant capacity.Protoplasma · 2022Article
- Identification and characterization of eight metallothionein genes involved in heavy metal tolerance from the ectomycorrhizal fungus Laccaria bicolor.Environmental science and pollution research international · 2022Article
- Genome-wide analysis of metallothionein gene family in maize to reveal its role in development and stress resistance to heavy metal.Biological research · 2022Article
- Genomics and transcriptomics to protect rice (Frontiers in plant science · 2022Review
- Drought stress tolerance mechanisms and their potential common indicators to salinity, insights from the wild watermelonFrontiers in plant science · 2022Review
- Identification of Candidate Genes for Salinity and Anaerobic Tolerance at the Germination Stage in Rice by Genome-Wide Association Analyses.Frontiers in genetics · 2022Article
- Review
- How do rice seedlings of landrace Pokkali survive in saline fields after transplantation? Physiology, biochemistry, and photosynthesis.Photosynthesis research · 2021Article
- Genome-Wide Identification and Analysis of the Metallothionein Genes inInternational journal of molecular sciences · 2021Article
- Elucidating the Response of Crop Plants towards Individual, Combined and Sequentially Occurring Abiotic Stresses.International journal of molecular sciences · 2021Review
- High-resolution genome-wide association study pinpoints metal transporter and chelator genes involved in the genetic control of element levels in maize grain.G3 (Bethesda, Md.) · 2021Article
- The Rice GLYCINE-RICH PROTEIN 3 Confers Drought Tolerance by Regulating mRNA Stability of ROS Scavenging-Related Genes.Rice (New York, N.Y.) · 2021Article
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMetallothioneins (MT) are low molecular weight, cysteine rich metal binding proteins, found across genera and species, but their function(s) in abiotic stress tolerance are not well documented.
resultsWe have characterized a rice MT gene, OsMT1e-P, isolated from a subtractive library generated from a stressed salinity tolerant rice genotype, Pokkali. Bioinformatics analysis of the rice genome sequence revealed that this gene belongs to a multigenic family, which consists of 13 genes with 15 protein products. OsMT1e-P is located on chromosome XI, away from the majority of other type I genes that are clustered on chromosome XII. Various members of this MT gene cluster showed a tight co-regulation pattern under several abiotic stresses. Sequence analysis revealed the presence of conserved cysteine residues in OsMT1e-P protein. Salinity stress was found to regulate the transcript abundance of OsMT1e-P in a developmental and organ specific manner. Using transgenic approach, we found a positive correlation between ectopic expression of OsMT1e-P and stress tolerance. Our experiments further suggest ROS scavenging to be the possible mechanism for multiple stress tolerance conferred by OsMT1e-P.
conclusionWe present an overview of MTs, describing their gene structure, genome localization and expression patterns under salinity and development in rice. We have found that ectopic expression of OsMT1e-P enhances tolerance towards multiple abiotic stresses in transgenic tobacco and the resultant plants could survive and set viable seeds under saline conditions. Taken together, the experiments presented here have indicated that ectopic expression of OsMT1e-P protects against oxidative stress primarily through efficient scavenging of reactive oxygen species.
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