ArticleJournal of the American Chemical Society2012
Reversible light switch for macrocycle mobility in a DNA rotaxane.
Article in Journal of the American Chemical Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Omega Nucleic Acids (ΩNA), Ultimate Nucleic Acids for Future Technology.Molecules (Basel, Switzerland) · 2026Review
- Synthetic dynamic transcription frameworks and their applications.Nature chemistry · 2026Review
- Light-activated CRISPR-Cas12a for amplified imaging of microRNA in cell cycle phases at single-cell levels.Science advances · 2024Article
- Phototriggered Equilibrated and Transient Orthogonally Operating Constitutional Dynamic Networks Guiding Biocatalytic Cascades.Journal of the American Chemical Society · 2024Article
- PhotocleavableChemical reviews · 2023Review
- Sliding Dynamics of Ring Chains on Two Asymmetric/Symmetric Chains in a Simple Slide-Ring Gel.Polymers · 2021Article
- DNA Assembly-Based Stimuli-Responsive Systems.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- Aptamer-Functionalized Hybrid Nanostructures for Sensing, Drug Delivery, Catalysis and Mechanical Applications.International journal of molecular sciences · 2021Review
- Interlocked DNA Nanojoints for Reversible Thermal Sensing.Angewandte Chemie (International ed. in English) · 2020Article
- Dynamic DNA Assemblies in Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Review
- Design, assembly, characterization, and operation of double-stranded interlocked DNA nanostructures.Nature protocols · 2019Article
- Structural optimization of pseudorotaxane-forming oligonucleotides for efficient and stable complex formation.Nucleic acids research · 2018Article
- Cyclization of secondarily structured oligonucleotides to single-stranded rings by usingRSC advances · 2018Article
- Supramolecular aptamer nano-constructs for receptor-mediated targeting and light-triggered release of chemotherapeutics into cancer cells.Nature communications · 2018Article
- Fabrication of circular assemblies with DNA tetrahedrons: from static structures to a dynamic rotary motor.Nucleic acids research · 2017Article
- Pseudorotaxane formation via the slippage process with chemically cyclized oligonucleotides.Nucleic acids research · 2017Article
- Programmable i-motif DNA folding topology for a pH-switched reversible molecular sensing device.Nucleic acids research · 2017Article
- A DNA nanoswitch-controlled reversible nanosensor.Nucleic acids research · 2017Article
- DNA Origami Rotaxanes: Tailored Synthesis and Controlled Structure Switching.Angewandte Chemie (International ed. in English) · 2016Article
- Long-range movement of large mechanically interlocked DNA nanostructures.Nature communications · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A recent trend in DNA nanotechnology consists of the assembly of architectures with dynamic properties that can be regulated by employing external stimuli. Reversible processes are important for implementing molecular motion into DNA architectures as they allow for the regeneration of the original state. Here we describe two different approaches for the reversible switching of a double-stranded DNA rotaxane architecture from a stationary pseudorotaxane mode into a state with movable components. Both states only marginally differ in their respective topologies but their mechanical properties are fundamentally different. In the two approaches, the switching operation is based on strand-displacement reactions. One of them employs toehold-extended oligodeoxynucleotides whereas in the other one the switching is achieved by light-irradiation. In both cases, multiple back and forth switching between the stationary and the mobile states was achieved in nearly quantitative fashion. The ability to reversibly operate mechanical motion in an interlocked DNA nanostructure opens exciting new avenues in DNA nanotechnology.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.